Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,752 questions · 6,648 findings · 688 reviews

No studies found 1,125 · 16.9%GRADE not reported 670 · 10.1%Very low 1,796 · 27%Low 1,685 · 25.3%Moderate 1,075 · 16.2%High 297 · 4.5%

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Intervention not reported

Aldosterone antagonists plus loop diuretics (1 RCT; 41 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (1 RCT; 41 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Paracentesis plus systemic vasoconstrictors (4 RCTs; 145 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes paracentesis plus systemic vasoconstrictors (4 RCTs; 145 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (2 RCT; 84 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (2 RCT; 84 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (1 RCT; 31 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (1 RCT; 31 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Paracentesis plus systemic vasoconstrictors (1 RCT; 25 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes paracentesis plus systemic vasoconstrictors (1 RCT; 25 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Transjugular intrahepatic portosystemic shunt (6 RCTs; 427 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes transjugular intrahepatic portosystemic shunt (6 RCTs; 427… (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (3 RCTs; 125 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (3 RCTs; 125 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Transjugular intrahepatic portosystemic shunt (6 RCTs; 392 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes transjugular intrahepatic portosystemic shunt (6 RCTs; 392… (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (4 RCTs; 211 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (4 RCTs; 211 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus paracentesis plus fluid replacement (1 RCT; 36 participants) · people with liver cirrhosis and ascites

The intervention may leads to higher aldosterone antagonists plus paracentesis plus fluid replacement (1… (low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (4 RCTs; 242 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (4 RCTs; 242 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Paracentesis plus systemic vasoconstrictors (3 RCTs; 114 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes paracentesis plus systemic vasoconstrictors (3 RCTs; 114 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Paracentesis plus systemic vasoconstrictors (5 RCTs; 165 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes paracentesis plus systemic vasoconstrictors (5 RCTs; 165 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics plus paracentesis plus fluid replacement (No direct RCT) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus paracentesis plus… (very low certainty).

1 finding from 1 review