Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,751 questions · 12,775 findings · 807 reviews · Headline outcomes only

No studies found 3,413 · 26.7%GRADE not reported 709 · 5.5%Very low 3,483 · 27.3%Low 3,165 · 24.8%Moderate 1,628 · 12.7%High 377 · 3%

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Alarm plus other intervention vs other interventions

Proportion of children dry at · children with nocturnal enuresis

Alarm plus other intervention showed no clear difference in proportion of children dry at compared with other intervention (low certainty).

2 findings from 1 review

Alarm vs placebo drug

Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis

Alarm may leads to higher proportion of children achieving 14 consecutive dry nights by the… compared with placebo drug (low certainty).

1 finding from 1 review

Intervention not reported

Death at one year · adults with renal vasculitis

The intervention showed no clear difference in death at one year (low certainty).

1 finding from 1 review

Pulse cyclophosphamide vs continuous cyclophosphamide

Recurrence of hyperthyroidism (relapse) [measured by serum thyroid hormone levels above the normal range after withdrawal of methimazole or end of radioiodine treatment] · adults with renal vasculitis

Pulse cyclophosphamide may leads to higher relapse at the end of compared with continuous cyclophosphamide (low certainty).

1 finding from 1 review

Intervention not reported

Serum creatinine at 1 year · adults with renal vasculitis
1 finding from 1 review