Hearing ‐ unclear · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
1 finding from 1 review
Serious complications ‐ mastoid abscess measured at 12 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
It is very uncertain whether systemic antibiotics changes serious complications ‐ mastoid abscess measured at 12 weeks compared with no treatment or placebo on top of topical antibiotics (very low certainty).
1 finding from 1 review
Suspected ototoxicity · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Resolution of ear discharge ‐ measured at 1 to 2 weeks · schoolchildren with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Resolution of ear discharge ‐ measured after 4 weeks · schoolchildren with CSOM
It is very uncertain whether systemic antibiotics changes resolution of ear discharge (4 weeks or more) ‐ measured at 3 to 4… compared with no treatment or placebo on top of topical antiseptics (very low certainty).
1 finding from 1 review
Health‐related quality of life · schoolchildren with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Ear pain (otalgia) or discomfort or local irritation · schoolchildren with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Hearing · schoolchildren with CSOM
1 finding from 1 review
Serious complications · schoolchildren with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Suspected ototoxicity · schoolchildren with CSOM
1 finding from 1 review
Health‐related quality of life · children with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Ear pain (otalgia) or discomfort or local irritation · children with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Hearing · children with CSOM
1 finding from 1 review
Serious complications ‐ during 6 months of · children with CSOM
1 finding from 1 review
Suspected ototoxicity · children with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Resolution of ear discharge ‐ measured at 1 to 2 weeks · people (of any age) with CSOM
Systemic antibiotics showed no clear difference in resolution of ear discharge ‐ measured at 1 to 2 weeks compared with no treatment or placebo on top of topical antibiotics (low certainty).
1 finding from 1 review
Resolution of ear discharge ‐ measured after 4 weeks · people (of any age) with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
FEV1 % predicted: relative change from baseline · adults and children with CF
1 finding from 1 review
Time to next exacerbation · adults and children with CF
1 finding from 1 review
Participants hospitalised for respiratory exacerbation · adults and children with CF
Summary of findings ‐ AZLI showed no clear difference in participants hospitalised for respiratory exacerbation compared with placebo (moderate certainty).
1 finding from 1 review