Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Intervention not reported

Transjugular intrahepatic portosystemic shunt (6 RCTs; 392 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes transjugular intrahepatic portosystemic shunt (6 RCTs; 392… (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (4 RCTs; 211 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (4 RCTs; 211 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus paracentesis plus fluid replacement (1 RCT; 36 participants) · people with liver cirrhosis and ascites

The intervention may leads to higher aldosterone antagonists plus paracentesis plus fluid replacement (1… (low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (4 RCTs; 242 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (4 RCTs; 242 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Paracentesis plus systemic vasoconstrictors (3 RCTs; 114 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes paracentesis plus systemic vasoconstrictors (3 RCTs; 114 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Paracentesis plus systemic vasoconstrictors (5 RCTs; 165 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes paracentesis plus systemic vasoconstrictors (5 RCTs; 165 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics plus paracentesis plus fluid replacement (No direct RCT) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus paracentesis plus… (very low certainty).

1 finding from 1 review

Intervention not reported

Transjugular intrahepatic portosystemic shunt (7 RCTs; 452 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes transjugular intrahepatic portosystemic shunt (7 RCTs; 452… (very low certainty).

1 finding from 1 review