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What do systematic reviews say?

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Evidence found and GRADE certainty

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Natural cycle vs programmed cycle

Clinical pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

It is very uncertain whether natural cycle changes clinical pregnancy rate compared with programmed cycle (very low certainty).

1 finding from 1 review