Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,532 questions · 2,642 findings · 483 reviews · Headline outcomes only

No studies found 534 · 20.2%GRADE not reported 82 · 3.1%Very low 641 · 24.3%Low 807 · 30.5%Moderate 472 · 17.9%High 106 · 4%

Angiotensin‐converting enzyme inhibitors vs conventional therapy

Cardiac events (fatal) · patients receiving PD

Angiotensin‐converting enzyme inhibitors (ACEi) showed no clear difference in cardiac events (fatal) compared with conventional therapy (moderate certainty).

1 finding from 1 review

Angiotensin‐converting enzyme inhibitors vs conventional therapy

Cardiac events (non fatal) · patients receiving PD

Angiotensin‐converting enzyme inhibitors (ACEi) showed no clear difference in cardiac events (non fatal) compared with conventional therapy (moderate certainty).

1 finding from 1 review

Angiotensin‐converting enzyme inhibitors vs conventional therapy

Peritonitis · patients receiving PD

Angiotensin‐converting enzyme inhibitors (ACEi) showed no clear difference in adverse events (episodes of peritonitis) compared with conventional therapy (moderate certainty).

1 finding from 1 review

Angiotensin‐converting enzyme inhibitors vs conventional therapy

Adverse events (episodes of peritonitis) ‐ treated with an aminoglycoside · patients receiving PD

Angiotensin‐converting enzyme inhibitors (ACEi) showed no clear difference in adverse events (episodes of peritonitis) ‐ treated with an… compared with conventional therapy (moderate certainty).

1 finding from 1 review

Angiotensin‐converting enzyme inhibitors vs conventional therapy

Adverse events (episodes of peritonitis) ‐ not treated with an aminoglycoside · patients receiving PD

Angiotensin‐converting enzyme inhibitors (ACEi) showed no clear difference in adverse events (episodes of peritonitis) ‐ not treated with an… compared with conventional therapy (moderate certainty).

1 finding from 1 review

Angiotensin‐converting enzyme inhibitors vs placebo or no treatment

Cardiovascular mortality · patients with chronic heart failure with preserved ejection fraction

Angiotensin‐converting enzyme inhibitors (ACEIs) showed no clear difference in cardiovascular mortality (RR) compared with placebo or no treatment (moderate certainty).

1 finding from 1 review