Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

402 questions · 411 findings · 41 reviews · Headline outcomes only

No studies found 99 · 24.1%GRADE not reported 32 · 7.8%Very low 132 · 32.1%Low 112 · 27.3%Moderate 33 · 8%High 3 · 0.7%

Intervention not reported

Primary outcome 2: participant‐ or parent‐rated participant quality of life score at the end of active treatment Scales used: DLQI, IDQoL, Skindex‐29, CDLQI. On those scales, the higher the score, the more severely the quality of life is affected ... · male and female patients 0 to 55 years of age with physician‐diagnosed eczema
1 finding from 1 review

Intervention not reported

Primary outcome 2: participant‐ or parent‐rated family quality of life score at the end of active treatment Scale used: DFI, FDLQI. On those scales, the higher the score, the more severely the quality of life is affected Duration of · male and female patients 0 to 55 years of age with physician‐diagnosed eczema
1 finding from 1 review

Intervention not reported

Secondary outcome 4: global eczema severity score (total SCORAD) at the end of active treatment (Investigator‐rated eczema severity) Scale used: total SCORAD ranging from 0 to 103. The higher the score, the more severe the disease Duration of · male and female patients 0 to 55 years of age with physician‐diagnosed eczema
1 finding from 1 review

Intervention not reported

Secondary outcome 6: adverse events (gastrointestinal symptoms) during active treatment Duration of · male and female patients 0 to 55 years of age with physician‐diagnosed eczema

The intervention showed no clear difference in secondary outcome 6: adverse events (gastrointestinal symptoms)… (low certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality ( · people with hepatic encephalopathy

The intervention showed no clear difference in all‐cause mortality ( (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events ‐ Change of/or withdrawal from treatment ( · people with hepatic encephalopathy

It is very uncertain whether the intervention changes adverse events ‐ Change of/or withdrawal from treatment ( (very low certainty).

1 finding from 1 review

Intervention not reported

Quality of life ( · people with hepatic encephalopathy
1 finding from 1 review

Intervention not reported

Plasma ammonia concentration (final and change scores) (μmol/L) ( · people with hepatic encephalopathy
1 finding from 1 review

Intervention not reported

No‐recovery (incomplete resolution of clinical symptoms) ( · people with hepatic encephalopathy

The intervention probably leads to lower no‐recovery (incomplete resolution of clinical symptoms) ( (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events ‐ Overt hepatic encephalopathy ( · people with hepatic encephalopathy

The intervention may leads to lower adverse events ‐ Overt hepatic encephalopathy ( (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events ‐ Change of/or withdrawal from treatment ( · people with hepatic encephalopathy

It is very uncertain whether the intervention changes adverse events ‐ Change of/or withdrawal from treatment ( (very low certainty).

1 finding from 1 review

Intervention not reported

Quality of life ( · people with hepatic encephalopathy
1 finding from 1 review

Intervention not reported

Plasma ammonia concentration (final and change scores) (μmol/L) ( · people with hepatic encephalopathy
1 finding from 1 review

Intervention not reported

All‐cause mortality ( · people with hepatic encephalopathy

It is very uncertain whether the intervention changes all‐cause mortality ( (very low certainty).

1 finding from 1 review

Intervention not reported

No‐recovery (incomplete resolution of clinical symptoms) ( · people with hepatic encephalopathy

It is very uncertain whether the intervention changes no‐recovery (incomplete resolution of clinical symptoms) ( (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events ‐ Overt hepatic encephalopathy ( · people with hepatic encephalopathy

It is very uncertain whether the intervention changes adverse events ‐ Overt hepatic encephalopathy ( (very low certainty).

1 finding from 1 review