Minoxidil vs placebo
Adverse events · women with FPHL
Minoxidil showed no clear difference in adverse events compared with placebo (low certainty).
1 finding from 1 review
- RR 1.24 [0.82, 1.87]4 studies · 727 participantsLow
Findings
What do systematic reviews say?
628 questions · 651 findings · 39 reviews · Skin
No studies found 167 · 25.7%GRADE not reported 47 · 7.2%Very low 80 · 12.3%Low 139 · 21.4%Moderate 174 · 26.7%High 44 · 6.8%
Minoxidil vs placebo
Proportion of participants with investigator‐rated clinically significant hair regrowth · women with FPHL
Minoxidil probably leads to higher proportion of participants with investigator‐rated clinically… compared with placebo (moderate certainty).
1 finding from 1 review
- RR 2.35 [1.68, 3.28]7 studies · 1181 participantsModerate
Minoxidil vs placebo
Change from baseline to study conclusion in total hair count · women with FPHL
1 finding from 1 review
- no estimate extracted8 studies · 1242 participantsLow
Minoxidil vs placebo
Degree of hair shedding from baseline to the end of the study · women with FPHL
1 finding from 1 review
- no estimate extracted3 studies · 380 participantsVery low
Minoxidil vs placebo
Cosmetic appearance of the hair or participant satisfaction · women with FPHL
1 finding from 1 review
- no estimate extracted1 study · 260 participantsLow
Minoxidil vs placebo
Change in quality (or pattern) of hair regrowth (e.g. thickness) · women with FPHL
1 finding from 1 review
- no estimate extracted2 studies · 372 participantsLow
Light therapies (including photodynamic therapy) vs placebo, no treatment, topical treatment and other comparators
Participant's global assessment of improvement Non‐standardised scale5 · Mild, moderate and severe acne vulgaris
1 finding from 1 review
- no estimate extracted23 studies · 1033 participantsVery low
Light therapies (including photodynamic therapy) vs placebo, no treatment, topical treatment and other comparators
Lesion count · Mild, moderate and severe acne vulgaris
1 finding from 1 review
- no estimate extracted51 studies · 2242 participantsVery low
Light therapies (including photodynamic therapy) vs placebo, no treatment, topical treatment and other comparators
Investigator‐assessed severe adverse effects Blistering or scarring · Mild, moderate and severe acne vulgaris
1 finding from 1 review
- no estimate extracted66 studies · 3945 participantsVery low
Chemical peeling vs placebo or no treatment
Participant‐reported scar improvement (long‐term) · people with acne scars
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Chemical peeling vs placebo or no treatment
Participant‐reported scar improvement (short‐term) · people with acne scars
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Chemical peeling vs placebo or no treatment
Investigator‐assessed adverse events (short‐term) · people with acne scars
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Chemical peeling vs placebo or no treatment
Participant‐assessed adverse events (short‐term) · people with acne scars
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Chemical peeling vs placebo or no treatment
Participant satisfaction · people with acne scars
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Chemical peeling vs placebo or no treatment
Quality of life · people with acne scars
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Chemical peeling vs placebo or no treatment
Serious or severe adverse events N of participants with positive severe adverse events · people with acne scars
It is very uncertain whether chemical peeling changes serious or severe adverse events N of participants with positive… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
- RR 5.45 [0.33, 90.14]1 study · 58 participantsVery low
Injectable fillers vs placebo or no treatment
Participant‐reported scar improvement (long‐term) · people with acne scars
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Injectable fillers vs placebo or no treatment
Participant‐reported scar improvement (short‐term) N of participants with > 50% improvement in acne scars · people with acne scars
Injectable fillers probably leads to higher participant‐reported scar improvement (short‐term) N of participants… compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
- RR 1.84 [1.31, 2.59]1 study · 147 participantsModerate
Injectable fillers vs placebo or no treatment
Patient satisfaction Number of satisfied patients · people with acne scars
Injectable fillers probably leads to higher participant satisfaction N of satisfied participants compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
- RR 1.63 [1.23, 2.15]1 study · 147 participantsModerate
Injectable fillers vs placebo or no treatment
Participant‐assessed adverse events (short‐term) N of participants with positive adverse events · people with acne scars
Injectable fillers showed no clear difference in participant‐reported adverse events (short‐term) N of participants… compared with placebo or no treatment (low certainty).
1 finding from 1 review
- RR 1.03 [0.1, 11.1]1 study · 147 participantsLow