Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

828 questions · 1,007 findings · 63 reviews · Oral Health

No studies found 110 · 10.9%GRADE not reported 709 · 70.4%Very low 84 · 8.3%Low 70 · 7%Moderate 33 · 3.3%High 1 · 0.1%

Electrofulguration + calcium hydroxide (CH) vs Electrofulguration + zinc oxide and eugenol (ZOE)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Electrofulguration + calcium hydroxide (CH) showed no clear difference in clinical failure compared with electrofulguration + zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Biodentine vs Diode laser

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 months
    Assessed pain, soft tissue, mobility, radiolucency, root resorption, premature tooth loss (Niranjani 2015); no clinical/radiological failure outcome; RR 2.00 (0.20 to 20.33)
    1 study · 40 participants
    GRADE not reported

Metapex (calcium hydroxide/iodoform) vs RC Fill (ZOE with iodoform)

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review

Self-etch adhesive + acetone-based total-etch adhesive vs Calcium hydroxide (CH)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes clinical failure compared with calcium hydroxide (CH) (very low certainty).

1 finding from 1 review

Calcium-enriched mixture (CEM) cement vs Mineral trioxide aggregate (MTA)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
2 findings from 1 review

Biodentine vs Tempophore

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Biodentine showed no clear difference in clinical failure compared with tempophore; GRADE not reported.

1 finding from 1 review

Total-etching 36% phosphoric acid + acetone-based total-etch adhesive vs Non-rinse conditioner + acetone-based total-etch adhesive

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes clinical failure compared with non-rinse conditioner + acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

ProRoot MTA vs OrthoMTA

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

ProRoot MTA showed no clear difference in clinical failure compared with orthoMTA; GRADE not reported.

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs Buffered glutaraldehyde

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 months
    Assessed pain, soft tissue, mobility, radiolucency, root resorption, pulp canal obliteration (Goyal 2016); no clinical/radiological failure outcome; pain, mobility, radiolucency, root resorption significantly favour MTA
    1 study · 60 participants
    GRADE not reported

Mineral trioxide aggregate (MTA) vs Diode laser

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 months
    Assessed pain, soft tissue, mobility, radiolucency, root resorption, premature tooth loss (Niranjani 2015); no clinical/radiological failure outcome; no significant differences (RR 0.33, 0.01 to 7.72)
    1 study · 40 participants
    GRADE not reported