Findings

What do systematic reviews say?

958 questions · 991 findings · 123 reviews · Headline outcomes only

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No studies found 177 · 17.9%GRADE not reported 25 · 2.5%Very low 230 · 23.2%Low 321 · 32.4%Moderate 185 · 18.7%High 53 · 5.3%

Bisphosphonate treatment (oral or intravenous) vs placebo or no treatment

Change in BAP (assessed 4 to 6 months post‐intervention) · children under the age of 18 with cerebral palsy (GMFCS levels III to V)

1 finding from 1 review

Bisphosphonate use in children with cerebral palsy 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 32 participants
Very low

Summary of findings table ‐ Intravenous paracetamol vs ultracaine paracervical block

Pain with dilation ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation

The review found no eligible studies for this question.

1 finding from 1 review

Local anaesthesia for pain control in first trimester surgical abortion 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Intravenous paracetamol vs ultracaine paracervical block

Pain with aspiration ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation

The review found no eligible studies for this question.

1 finding from 1 review

Local anaesthesia for pain control in first trimester surgical abortion 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Intravenous paracetamol vs ultracaine paracervical block

Pain during procedurea,b · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation

1 finding from 1 review

Local anaesthesia for pain control in first trimester surgical abortion 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 46 participants
Moderate

Consumption of intravenous morphine equivalents (mg): PCA vs non‐patient controlled opioid analgesia

Consumption of morphine equivalents 0 to 24 hmg · patients with postoperative pain

1 finding from 1 review

Patient controlled opioid analgesia versus non‐patient controlled opioid analgesia for postoperative pain 2015 · Cochrane Headline outcomes only
no estimate extracted
25 studies · 1586 participants
Low

Consumption of intravenous morphine equivalents (mg): PCA vs non‐patient controlled opioid analgesia

Consumption of morphine equivalents 25 to 48 hmg · patients with postoperative pain

1 finding from 1 review

Patient controlled opioid analgesia versus non‐patient controlled opioid analgesia for postoperative pain 2015 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 449 participants
Moderate

Consumption of intravenous morphine equivalents (mg): PCA vs non‐patient controlled opioid analgesia

Consumption of morphine equivalents 0 to 48 hmg · patients with postoperative pain

1 finding from 1 review

Patient controlled opioid analgesia versus non‐patient controlled opioid analgesia for postoperative pain 2015 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 334 participants
Very low

Consumption of intravenous morphine equivalents (mg): PCA vs non‐patient controlled opioid analgesia

Consumption of morphine equivalents 0 to 72 hmg · patients with postoperative pain

1 finding from 1 review

Patient controlled opioid analgesia versus non‐patient controlled opioid analgesia for postoperative pain 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 244 participants
Very low

Summary of findings table ‐ Intravenous paracetamol 1000 mg vs 2 pumps of cervical lidocaine spray

Pain with dilation ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation

The review found no eligible studies for this question.

1 finding from 1 review

Local anaesthesia for pain control in first trimester surgical abortion 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Intravenous paracetamol 1000 mg vs 2 pumps of cervical lidocaine spray

Pain with aspiration ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation

The review found no eligible studies for this question.

1 finding from 1 review

Local anaesthesia for pain control in first trimester surgical abortion 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Intravenous paracetamol 1000 mg vs 2 pumps of cervical lidocaine spray

Pain during procedurea,b · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation

1 finding from 1 review

Local anaesthesia for pain control in first trimester surgical abortion 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Low

Erythropoietin (subcutaneous or intravenous at varying dosages) vs placebo

Health‐related quality of life · anemia in patients with rheumatoid arthritis

1 finding from 1 review

Erythropoiesis‐stimulating agents for anemia in rheumatoid arthritis 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 136 participants
Very low

Erythropoietin (subcutaneous or intravenous at varying dosages) vs placebo

Hemoglobin (Hb) level at the end of the study · anemia in patients with rheumatoid arthritis

1 finding from 1 review

Erythropoiesis‐stimulating agents for anemia in rheumatoid arthritis 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 116 participants
Low

Erythropoietin (subcutaneous or intravenous at varying dosages) vs placebo

Fatigue ‐ not reported · anemia in patients with rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Erythropoiesis‐stimulating agents for anemia in rheumatoid arthritis 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Erythropoietin (subcutaneous or intravenous at varying dosages) vs placebo

Adverse events and drug reactions · anemia in patients with rheumatoid arthritis

1 finding from 1 review

Erythropoiesis‐stimulating agents for anemia in rheumatoid arthritis 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 3 participants
Very low

Erythropoietin (subcutaneous or intravenous at varying dosages) vs placebo

Withdrawals due to adverse events · anemia in patients with rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Erythropoiesis‐stimulating agents for anemia in rheumatoid arthritis 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Erythropoietin (subcutaneous or intravenous at varying dosages) vs placebo

Lack of efficacy withdrawal · anemia in patients with rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Erythropoiesis‐stimulating agents for anemia in rheumatoid arthritis 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Erythropoietin (subcutaneous or intravenous at varying dosages) vs placebo

Withdrawals due to high blood pressure · anemia in patients with rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Erythropoiesis‐stimulating agents for anemia in rheumatoid arthritis 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Initial infusion rate of intravenous acetylcysteine over 15 minutes vs 60 minutes

All‐cause mortality · people with paracetamol (acetaminophen) overdose

1 finding from 1 review

Interventions for paracetamol (acetaminophen) overdose 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 180 participants
Very low

Initial infusion rate of intravenous acetylcysteine over 15 minutes vs 60 minutes

Hepatotoxicity · people with paracetamol (acetaminophen) overdose

It is very uncertain whether initial infusion rate of intravenous acetylcysteine over 15 minutes changes hepatotoxicity compared with 60 minutes (very low certainty).

1 finding from 1 review

Interventions for paracetamol (acetaminophen) overdose 2018 · Cochrane Headline outcomes only
OR 1.34 [0.39, 4.56]
1 study · 175 participants
Very low