Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,125 questions · 1,173 findings · 91 reviews · Headline outcomes only

No studies found 192 · 16.4%GRADE not reported 47 · 4%Very low 199 · 17%Low 325 · 27.7%Moderate 271 · 23.1%High 139 · 11.8%

Rapid COJEC vs standard induction therapies

Early toxicities (during preoperative chemotherapy): febrile neutropenia (2 or more episodes), proven fungal infections, septicemia (1 or more episodes), gastrointestinal toxicity (grade 3 or 4), renal toxicity (glomerular filtration rate < 80 ml/... · patients with high‐risk neuroblastoma
1 finding from 1 review

Intervention not reported

the toxic and side effects in digestive system after chemotherapy (no special data in trial of Zhang 2006) · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects in digestive system after chemotherapy… (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects in digestive system after chemotherapy · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects in digestive system after chemotherapy (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects of leukopenia after chemotherapy · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects of leukopenia after chemotherapy (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects of leukopenia after chemotherapy(no special data in trial of Zhang 2006) · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects of leukopenia after chemotherapy(no… (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects in digestive system after chemotherapy · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects in digestive system after chemotherapy (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects of leukopenia after chemotherapy(no special data in trial of Jia 2003, Zhang 2009) · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects of leukopenia after chemotherapy(no… (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects in digestive system after chemotherapy(no special data in trial of Fu 2011, Liu 2009a, Zhang 2010) · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects in digestive system after chemotherapy(no… (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects of leukopenia after chemotherapy · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects of leukopenia after chemotherapy (very low certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality at 31 to 100 days · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

It is very uncertain whether the intervention changes all‐cause mortality at 31 to 100 days (very low certainty).

1 finding from 1 review

Intervention not reported

Number of participants with any bleeding ‐ not reported · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Length of hospital admission ‐ not reported · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Hospital readmission rate ‐ not reported · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Number of participants with any bleeding (0 to 3 months) · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The intervention showed no clear difference in number of participants with any bleeding (0 to 3 months) (low certainty).

1 finding from 1 review

Intervention not reported

Number of participants with clinically significant bleeding (0 to 3 months) · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The intervention showed no clear difference in number of participants with clinically significant bleeding (0 to 3… (low certainty).

1 finding from 1 review

Intervention not reported

Serious infections (0 to 3 months) · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The intervention showed no clear difference in serious infections (0 to 3 months) (low certainty).

1 finding from 1 review