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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

581 questions in 23 reviews · Implants and prosthodontics

current versions
No studies 87 · 15%Ungraded 388 · 66.8%Very low 88 · 15.1%Low 10 · 1.7%Moderate 8 · 1.4%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
ARP with xenograft (bone graft) vs Extraction alone
Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 36 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
1 trial (Cha 2019) reported delayed healing with partial exposure of the buccal plate at suture removal by 1 participant in the test group; another trial (Festa 2013) reported pain and swelling2 studies · 54 participantsLow
ARP with xenograft (bone graft) vs Extraction alone
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 36 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
RR 1.0 [0.07, 14.9]2 studies · 70 participantsVery low
ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15
Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
MD -0.87 [-1.61, -0.13]1 study · 18 participantsVery low
ARP with alloplast vs ARP with xenograft
Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 8 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
RR 1.09 [0.65, 1.83]2 studies · 37 participantsVery low
ARP with allograft vs ARP with xenograft
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane
Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 9 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast vs Extraction alone
Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with allograft vs ARP with xenograft
Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
MD -0.4 [-1.13, 0.34]3 studies · 87 participantsVery low
ARP with alloplast vs ARP with xenograft
Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 8 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
MD -0.6 [-1.27, 0.07]1 study · 25 participantsVery low
ARP with alloplast vs Extraction alone
Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast vs ARP with xenograft
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 8 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane
Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 9 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Fibrous adhesions at the cervical part of previously preserved sockets were observed in 2 participants (Brkovic 2012)1 study · 20 participantsVery low
ARP with alloplast vs Extraction alone
Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
MD -3.73 [-4.05, -3.41]1 study · 15 participantsVery low
ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15
Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Included study (Fernandes 2011) reported there were no adverse effects1 study · 18 participantsVery low
ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane
Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 9 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
MD 0.43 [0.18, 0.68]1 study · 20 participantsVery low
ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15
Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast vs Extraction alone
Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Included study (Madan 2014) reported there were no adverse effects1 study · 15 participantsVery low
ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15
Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
MD -0.3 [-1.06, 0.46]1 study · 18 participantsVery low
ARP with xenograft (bone graft) vs Extraction alone
Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 36 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
RR 0.68 [0.29, 1.62]4 studies · 154 participantsVery low
ARP with allograft vs ARP with xenograft
Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
RR 6.36 [0.35, 115.73]1 study · 40 participantsVery low
ARP with alloplast vs ARP with xenograft
Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 8 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
1 trial (Patel 2013) reported pain, swelling, membrane exposure and partial loss of grafting material, while the other trial (Gholami 2012) reported that the procedure was uneventful2 studies · 37 participantsLow
ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 9 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with alloplast vs ARP with xenograft
Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 8 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
MD -0.31 [-0.66, 0.04]2 studies · 37 participantsVery low
ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size
Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
MD 0.1 [-0.97, 1.17]1 study · 30 participantsVery low
ARP with alloplast vs ARP with xenograft
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 8 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Not estimable; 1 trial (Patel 2013) reported that none of the implants failed after 12 months of loading1 study · 25 participantsVery low
ARP with allograft vs ARP with xenograft
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size
Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months
Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane
Outcome not reported0 studiesNo studies
Tooth- and tissue-supported removable partial denture: dual-impression technique with a different material vs An alternative dual-impression technique with a different material
Outcome NR · Partially edentulous people requiring a tooth- and tissue-supported (distal-extension) removable partial denture
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
We did not find any trials for this comparison.0 studiesNo studies
Alginate (two stage-two step final/wash impression) vs Silicone elastomer (two stage-two step)
Number of border adjustments and sore spots after insertion of denture · Completely edentulous people
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
Not measured0 studiesNo studies
Altered-cast impression technique (ACIP), polyether vs One-piece cast technique (OPC), polyether
Operator-assessed gingival health of abutment · Partially edentulous people requiring a tooth- and tissue-supported (distal-extension) removable partial denture · 1 year, left abutment
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
RR 1.10 [0.46, 2.64]1 studyVery low
Single-stage alginate impression (simplified method) vs Two stage-two step zinc-oxide eugenol (ZoE) traditional method
Participant-reported quality of the denture (general satisfaction) · Completely edentulous people · 6 months
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
RR 3.15 [0.14, 72.88]1 study · 39 participantsVery low
Ball (stud) attachment system vs Bar attachment system
Re-treatment: replacement of attachment system (short term) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures) · Short term (1 to 3 years)
Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane
RR 1.18 [0.38, 3.71]2 studies · 130 participantsVery low
Ball (stud) attachment system vs Magnetic attachment system
Cost of prosthodontic maintenance (medium term) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures) · Medium term (3 to 5 years)
Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane
MD -247.37 [-346.32, -148.42]1 study · 69 participantsVery low
Single-stage alginate impression (simplified method) vs Two stage-two step zinc-oxide eugenol (ZoE) traditional method
Number of border adjustments and sore spots after insertion of denture · Completely edentulous people
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
Not measured0 studiesNo studies
Ball (stud) attachment system vs Magnetic attachment system
Prosthodontic success (medium term) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures) · Medium term (3 to 5 years)
Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane
RR 0.84 [0.64, 1.10]1 study · 69 participantsVery low
Ball (stud) attachment system vs Telescopic attachment system
Prosthodontic success (specific categorization) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures) · Short term (1 to 3 years)
Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane
no estimate extractedNRNo studies
Single-stage alginate impression (simplified method) vs Two stage-two step elastomer (silicone, polysulfide, or polyether) conventional method
Operator-assessed quality of the denture · Completely edentulous people · 6 months
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
There was insufficient evidence of a clear difference between groups at six-month follow-up in operator-assessed quality of the dentures (Kawai 2005).1 studyUngraded
Altered-cast impression technique (ACIP), polyether vs One-piece cast technique (OPC), polyether
Denture base adaptation (buccal shelf and ridge crest) · Partially edentulous people requiring a tooth- and tissue-supported (distal-extension) removable partial denture · 1 year
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
MD -0.11 [-0.18, -0.04]1 studyUngraded
Wax (fluid wax), two stage-two step selective pressure final impression vs Polysulfide rubber (elastomer)
Participant-reported oral health-related quality of life (OHIP-EDENT) · Completely edentulous people
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
Not measured0 studiesNo studies
Wax (fluid wax), two stage-two step selective pressure final impression vs Polysulfide rubber (elastomer)
Participant-reported quality of the denture · Completely edentulous people
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
Not measured0 studiesNo studies
Ball (stud) attachment system vs Bar attachment system
Re-treatment: repair of attachment system (short term) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures) · Short term (1 to 3 years)
Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane
RR 3.11 [1.68, 5.75]2 studies · 130 participantsVery low
Ball (stud) attachment system vs Bar attachment system
Prosthodontic success (short term) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures) · Short term (1 to 3 years)
Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane
Considerable heterogeneity (I2 = 97%). Pooling of data was not done. See comment / See comment2 studies · 130 participantsVery low
Selective pressure final-impression technique (two stage-two step, silicone elastomer) vs Traditional technique (redistributing pressure) and control technique (relatively mucostatic standard procedure)
Participant preference for dentures · Completely edentulous people · 4 to 5 weeks
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
33 participants chose dentures made using the selective pressure technique, 19 chose the traditionally-made denture and 14 chose the control denture. There was no clear preference between the traditional and control…1 study · 69 participantsLow
Biofunctional Prosthetic System (BPS): closed-mouth two stage-two step final impression with addition silicone elastomer vs Conventional complete denture technique (CCD): open-mouth two stage-two step conventional technique using elastomer
Participant-reported oral health-related quality of life (OHIP-EDENT) · Completely edentulous people · 3 months
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
OHIP-EDENT median scores: BPS 34.5; CCD 35.8. No clear difference between groups1 study · 10 participantsVery low
Biofunctional Prosthetic System (BPS): closed-mouth two stage-two step final impression with addition silicone elastomer vs Conventional complete denture technique (CCD): open-mouth two stage-two step conventional technique using elastomer
Number of border adjustments and sore spots after insertion of denture · Completely edentulous people · 3 months
Final‐impression techniques and materials for making complete and removable partial dentures (2018) · Cochrane
Median number of denture adjustments: BPS 3.5; CCD 4.5. BPS required fewer adjustments1 study · 10 participantsVery low
Ball (stud) attachment system vs Bar attachment system
Cost (treatment time and/or material costs) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)
Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (2018) · Cochrane
Walton 2002 reported costs but the data could not be used due to failure to report means and standard deviations and only providing the median of the costs.1 studyUngraded