Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

82 questions · 91 findings · 10 reviews · Headline outcomes only

No studies found 12 · 13.2%GRADE not reported 0 · 0%Very low 25 · 27.5%Low 31 · 34.1%Moderate 23 · 25.3%High 0 · 0%

Therapeutic contact lens vs topical lubrication

Resolution of symptoms · people with recurrent corneal erosion syndrome without previous surgical intervention

Therapeutic contact lens showed no clear difference in resolution of symptoms after treatment compared with topical lubrication (low certainty).

1 finding from 1 review

Therapeutic contact lens vs topical lubrication

Recurrence after complete or partial resolution · people with recurrent corneal erosion syndrome without previous surgical intervention

It is very uncertain whether therapeutic contact lens changes recurrence after complete or partial resolution compared with topical lubrication (very low certainty).

1 finding from 1 review

Phototherapeutic keratectomy vs alcohol delamination

Recurrences requiring further treatment · people with recurrent corneal erosion syndrome without previous surgical intervention

It is very uncertain whether phototherapeutic keratectomy changes recurrences requiring further treatment compared with alcohol delamination (very low certainty).

1 finding from 1 review

Phototherapeutic keratectomy vs alcohol delamination

Recurrence after complete or partial resolution · people with recurrent corneal erosion syndrome without previous surgical intervention

Phototherapeutic keratectomy showed no clear difference in recurrence after complete or partial resolution compared with alcohol delamination (low certainty).

1 finding from 1 review

Psychological therapy vs control intervention

Improvement in pain scores—Integrated approach (somatic, psychological, dietary, environmental and physiotherapeutic factors) versus standard care · women with chronic pelvic pain

Psychological therapy showed no clear difference in improvement in pain scores—Integrated approach (somatic,… compared with control interventions (low certainty).

1 finding from 1 review

Therapeutic community and aftercare vs cognitive behavioural skills

Criminal activity ‐ Re‐arrests · drug‐using women offenders with co‐occurring mental health problems

Therapeutic community and aftercare showed no clear difference in re‐arrest for any type of crime compared with cognitive behavioural skills (low certainty).

1 finding from 1 review