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What do systematic reviews say?

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Evidence found and GRADE certainty

40 questions · 48 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 27 · 56.3%Very low 4 · 8.3%Low 9 · 18.8%Moderate 5 · 10.4%High 3 · 6.3%

Summary of findings table ‐ Progestogens vs GnRH antagonists

Clinical pregnancy · assisted reproduction technology cycles

Summary of findings table ‐ Progestogens showed no clear difference in clinical pregnancy ‐ Poor‐responders (MPA 10 mg versus GnRH… compared with gnRH antagonists (low certainty).

1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH antagonists

Live birth or ongoing pregnancy ‐ Poor‐responders (MPA 10 mg versus GnRH antagonists) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles

Summary of findings table ‐ Progestogens showed no clear difference in live birth or ongoing pregnancy ‐ Poor‐responders (MPA 10 mg versus… compared with gnRH antagonists; GRADE not reported.

1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH agonist

Live birth or ongoing pregnancy · assisted reproduction technology cycles

Summary of findings table ‐ Progestagen showed no clear difference in live birth or ongoing pregnancy compared with gnRH agonist (low certainty).

1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH agonist

Oocyte pick‐up cancellation · assisted reproduction technology cycles

Summary of findings table ‐ Progestagen showed no clear difference in oocyte pick‐up cancellation compared with gnRH agonist (low certainty).

1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH agonist

Moderate or severe OHSS · assisted reproduction technology cycles

It is very uncertain whether summary of findings table ‐ Progestagen changes moderate or severe OHSS compared with gnRH agonist (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Progestogens vs Progestogen 2

Oocyte pick‐up cancellation · assisted reproduction technology cycles

Summary of findings table ‐ Progestogen 1 showed no clear difference in oocyte pick‐up cancellation ‐ Normo‐responders (MPA 4 mg versus… compared with progestogen 2 (low certainty).

5 findings from 1 review
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Summary of findings table ‐ Progestogens vs Progestogen 2

Oocyte pick‐up cancellation ‐ Normo‐responders (Dydrogesterone 20 mg versus Micronised progesterone 100 mg) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles

Summary of findings table ‐ Progestogen 1 showed no clear difference in oocyte pick‐up cancellation ‐ Normo‐responders (Dydrogesterone 20 mg… compared with progestogen 2 (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Progestogens vs Progestogen 2

Clinical pregnancy · assisted reproduction technology cycles

Summary of findings table ‐ Progestogen 1 showed no clear difference in clinical pregnancy ‐ Normo‐responders (MPA 10 mg versus… compared with progestogen 2 (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Progestogens vs Progestogen 2

Miscarriage · assisted reproduction technology cycles

Summary of findings table ‐ Progestogen 1 showed no clear difference in miscarriage ‐ Miscarriage per randomised woman ‐ Normo‐responders… compared with progestogen 2 (low certainty).

1 finding from 1 review