All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Povidone iodine rinse showed no clear difference in mortality compared with saline rinse or placebo; GRADE not reported.
1 finding from 1 review
Duration of mechanical ventilation · Critically ill patients receiving mechanical ventilation in ICU
Triclosan rinse led to lower duration of mechanical ventilation compared with saline rinse; GRADE not reported.
1 finding from 1 review
COVID-19 viral content of aerosol (when present) · Patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
Change in COVID-19 viral load at site(s) of irrigation · Patients without suspected or confirmed COVID-19 infection undergoing aerosol-generating procedures (AGPs), and the healthcare workers…
The review found no eligible studies for this question.
1 finding from 1 review
Anosmia (or disturbance in sense of smell) · Patients without suspected or confirmed COVID-19 infection undergoing aerosol-generating procedures (AGPs), and the healthcare workers…
The review found no eligible studies for this question.
1 finding from 1 review
Incidence of symptomatic or test-positive COVID-19 infection in HCWs or patients · Patients without suspected or confirmed COVID-19 infection undergoing aerosol-generating procedures (AGPs), and the healthcare workers…
The review found no eligible studies for this question.
1 finding from 1 review
Other adverse events (allergy, irritation/burning of nasal, oral or oropharyngeal mucosa, long-term staining of mucous membranes or teeth, accidental ingestion) · Patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
Changes in microbiome in oral cavity, nasal cavity, oro- or nasopharynx · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
Incidence of symptomatic or test-positive COVID-19 infection in HCWs · Patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
Triclosan rinse showed no clear difference in incidence of VAP compared with saline rinse; GRADE not reported.
1 finding from 1 review
Incidence of symptomatic or test-positive COVID-19 infection in HCWs · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
Anosmia (or disturbance in sense of smell) · Patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
Change in viral load · Patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
RECOVERY trial outcomes (mortality; hospitalisation status; use of ventilation; use of renal dialysis or haemofiltration) · Patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
Povidone iodine rinse led to lower incidence of VAP compared with saline rinse or placebo; GRADE not reported.
1 finding from 1 review
Duration of ICU stay · Critically ill patients receiving mechanical ventilation in ICU
Povidone iodine rinse showed no clear difference in duration of ICU stay compared with saline rinse or placebo; GRADE not reported.
1 finding from 1 review
Other adverse events (allergy, irritation/burning of nasal, oral or oropharyngeal mucosa, long-term staining of mucous membranes or teeth, accidental ingestion) · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
Changes in microbiome in oral cavity, nasal cavity, oro- or nasopharynx · Patients with suspected or confirmed COVID-19 infection
The review found no eligible studies for this question.
1 finding from 1 review
COVID-19 viral content of aerosol · Patients without suspected or confirmed COVID-19 infection undergoing aerosol-generating procedures (AGPs), and the healthcare workers…
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Adverse effects (Seguin 2014): no evidence of a difference in acute respiratory distress syndrome (RR 11.00, 95% CI 0.62 to 195.61), agitation and/or hypertension (RR 0.48, 95% CI 0.12 to 1.86), epistaxis (RR 0.14, 95%…
1 study
GRADE not reported