Findings

What do systematic reviews say?

22 questions · 24 findings · 1 reviews

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No studies found 4 · 16.7%GRADE not reported 0 · 0%Very low 2 · 8.3%Low 11 · 45.8%Moderate 7 · 29.2%High 0 · 0%

Regular‐dose postoperative 5‐Fluorouracil vs control

Failure at 12 months ‐ high risk of failure · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil probably leads to lower failure at 12 months ‐ high risk of failure compared with control (moderate certainty).

1 finding from 1 review

5‐Fluorouracil for glaucoma surgery 2014 · Cochrane Headline outcomes only
RR 0.44 [0.29, 0.68]
2 studies · 239 participants
Moderate

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ wound leak ‐ high risk of failure · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil probably leads to higher complications ‐ wound leak ‐ high risk of failure compared with control (moderate certainty).

1 finding from 1 review

5‐Fluorouracil for glaucoma surgery 2014 · Cochrane Headline outcomes only
RR 1.64 [1.04, 2.58]
2 studies · 239 participants
Moderate