Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

40 questions · 40 findings · 3 reviews · Hepato-Biliary

No studies found 8 · 20%GRADE not reported 1 · 2.5%Very low 15 · 37.5%Low 5 · 12.5%Moderate 9 · 22.5%High 2 · 5%

Microwave coagulation vs radiofrequency ablation

Recurrence of liver metastases local progression · people with liver metastases

It is very uncertain whether microwave coagulation changes recurrence of liver metastases local progression compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Microwave coagulation vs radiofrequency ablation

Recurrence of liver metastases distant recurrence · people with liver metastases

It is very uncertain whether microwave coagulation changes recurrence of liver metastases distant recurrence compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Laser ablation vs radiofrequency ablation

Cancer‐related mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether laser ablation changes cancer‐related mortality at maximal compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Laser ablation vs radiofrequency ablation

Serious adverse events (number of participants) · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether laser ablation changes serious adverse events (number of participants) compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Percutaneous ethanol injection vs radiofrequency ablation

Mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether percutaneous alcohol injection changes mortality at maximal compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Percutaneous ethanol injection vs radiofrequency ablation

Cancer‐related mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

Percutaneous alcohol injection may leads to higher cancer‐related mortality at maximal compared with radiofrequency ablation (low certainty).

1 finding from 1 review

Percutaneous ethanol injection vs radiofrequency ablation

Serious adverse events (number of participants) · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether percutaneous alcohol injection changes serious adverse events (number of participants) compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Percutaneous ethanol injection vs radiofrequency ablation

Serious adverse events (number of events) · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether percutaneous alcohol injection changes serious adverse events (number of events) compared with radiofrequency ablation (very low certainty).

1 finding from 1 review