Sputum culture conversion at 8 weeks · Patients with presumed drug‐sensitive TB
Fluoroquinolone substitution for isoniazid in a standard six month… showed no clear difference in sputum culture conversion at 8 weeks compared with standard regimen (low certainty).
1 finding from 1 review
Serious adverse events · Patients with presumed drug‐sensitive TB
Fluoroquinolone substitution for isoniazid in a standard six month… showed no clear difference in serious adverse events compared with standard regimen (low certainty).
1 finding from 1 review
One or more adverse event · Patients with presumed drug‐sensitive TB
1 finding from 1 review
Death from any cause · Patients with presumed drug‐sensitive TB
It is very uncertain whether fluoroquinolone substitution for ethambutol in a standard six month… changes death from any cause compared with standard regimen (very low certainty).
1 finding from 1 review
TB‐related death · Patients with presumed drug‐sensitive TB
It is very uncertain whether fluoroquinolone substitution for ethambutol in a standard six month… changes TB‐related death compared with standard regimen (very low certainty).
1 finding from 1 review
Sputum culture conversion at 8 weeks · Patients with presumed drug‐sensitive TB
It is very uncertain whether fluoroquinolone substitution for ethambutol in a standard six month… changes sputum culture conversion at 8 weeks compared with standard regimen (very low certainty).
1 finding from 1 review
Serious adverse events · Patients with presumed drug‐sensitive TB
It is very uncertain whether fluoroquinolone substitution for ethambutol in a standard six month… changes serious adverse events compared with standard regimen (very low certainty).
1 finding from 1 review
One or more adverse events · Patients with presumed drug‐sensitive TB
1 finding from 1 review
Treatment failure · Patients with presumed drug‐sensitive TB
1 finding from 1 review
Relapse · Patients with presumed drug‐sensitive TB
It is very uncertain whether fluoroquinolone substitution for ethambutol in a standard six month… changes relapse compared with standard regimen (very low certainty).
1 finding from 1 review
Intervention not reported
True positivespeople with fluoroquinolone resistance · adults with pulmonary tuberculosis irrespective of rifampicin resistance (i.e. whether or not their rifampicin resistance status was…
1 finding from 1 review
Intervention not reported
False negativespeople incorrectly classified as not having fluoroquinolone resistance · adults with pulmonary tuberculosis irrespective of rifampicin resistance (i.e. whether or not their rifampicin resistance status was…
1 finding from 1 review
Intervention not reported
True negativespeople without fluoroquinolone resistance · adults with pulmonary tuberculosis irrespective of rifampicin resistance (i.e. whether or not their rifampicin resistance status was…
1 finding from 1 review
Intervention not reported
False positivespeople incorrectly classified as having fluoroquinolone resistance · adults with pulmonary tuberculosis irrespective of rifampicin resistance (i.e. whether or not their rifampicin resistance status was…
1 finding from 1 review
Clinical failure · adults and children with enteric fever
Cefixime may leads to higher clinical failure compared with fluoroquinolones (low certainty).
1 finding from 1 review
Clinical failure · adults and children with enteric fever
It is very uncertain whether ceftriaxone changes clinical failure compared with fluoroquinolones (very low certainty).
1 finding from 1 review
Microbiological failure · adults and children with enteric fever
It is very uncertain whether ceftriaxone changes microbiological failure compared with fluoroquinolones (very low certainty).
1 finding from 1 review
Relapse · adults and children with enteric fever
It is very uncertain whether ceftriaxone changes relapse compared with fluoroquinolones (very low certainty).
1 finding from 1 review
Time to defervescence · adults and children with enteric fever
It is very uncertain whether ceftriaxone changes time to defervescence compared with fluoroquinolones (very low certainty).
1 finding from 1 review
Length of hospital stay · adults and children with enteric fever
1 finding from 1 review