Total failure: day 28 (unadjusted) · adults and children with uncomplicated P falciparum malaria
Pyronaridine‐artesunate (PY‐AS) may leads to lower total failure: day 28 (unadjusted) compared with artemether‐lumefantrine (AL) (low certainty).
2 findings from 1 review
Subsequent treatment(s), abnormal ALT increase · adults and children with uncomplicated malaria
Pyronaridine‐artesunate (PY‐AS) showed no clear difference in subsequent treatment(s), abnormal ALT increase compared with other antimalarials (low certainty).
1 finding from 1 review
Subsequent treatment(s), abnormal AST increase · adults and children with uncomplicated malaria
Pyronaridine‐artesunate (PY‐AS) showed no clear difference in subsequent treatment(s), abnormal AST increase compared with other antimalarials (low certainty).
1 finding from 1 review
Subsequent treatment(s), abnormal bilirubin increase · adults and children with uncomplicated malaria
Pyronaridine‐artesunate (PY‐AS) showed no clear difference in subsequent treatment(s), abnormal bilirubin increase compared with other antimalarials (low certainty).
1 finding from 1 review
Serious adverse events (42 days) · adults and children with uncomplicated P falciparum malaria
Pyronaridine‐artesunate (PY‐AS) showed no clear difference in serious adverse events (42 days) compared with artemether‐lumefantrine (AL) (low certainty).
1 finding from 1 review
First treatment, abnormal ALT increase (42 days) · adults and children with uncomplicated P falciparum malaria
Pyronaridine‐artesunate (PY‐AS) may leads to higher first treatment, abnormal ALT increase (42 days) compared with artemether‐lumefantrine (AL) (low certainty).
1 finding from 1 review
First treatment, abnormal AST increase (42 days) · adults and children with uncomplicated P falciparum malaria
Pyronaridine‐artesunate (PY‐AS) may leads to higher first treatment, abnormal AST increase (42 days) compared with artemether‐lumefantrine (AL) (low certainty).
1 finding from 1 review
First treatment, abnormal bilirubin increase (42 days) · adults and children with uncomplicated P falciparum malaria
Pyronaridine‐artesunate (PY‐AS) showed no clear difference in first treatment, abnormal bilirubin increase (42 days) compared with artemether‐lumefantrine (AL) (low certainty).
1 finding from 1 review
Outcomesa · adults and children with uncomplicated P falciparum malaria
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found