Findings

What do systematic reviews say?

226 questions · 230 findings · 12 reviews · Common Mental Disorders

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No studies found 54 · 23.5%GRADE not reported 7 · 3%Very low 80 · 34.8%Low 60 · 26.1%Moderate 22 · 9.6%High 7 · 3%

Opioid antagonists vs placebo

Time spent gambling ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Opioid antagonists vs placebo

Depressive symptoms · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 77 participants
Low

Opioid antagonists vs placebo

Anxiety · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 77 participants
Low

Opioid antagonists vs placebo

Functional impairment · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 77 participants
Low

Opioid antagonists vs placebo

Responder status · treatment of disordered and problem gambling

It is very uncertain whether opioid antagonists changes responder status compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
RR 1.65 [0.86, 3.14]
4 studies · 562 participants
Very low

Mood stabilisers vs placebo

Gambling symptom severity · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 71 participants
Very low

Mood stabilisers vs placebo

Gambling expenditure · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

Mood stabilisers vs placebo

Gambling frequency ‐ not measured · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

Antidepressants vs placebo

Gambling expenditure · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 144 participants
Low

Mood stabilisers vs placebo

Time spent gambling ‐ not measured · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

Mood stabilisers vs placebo

Depressive symptoms · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 71 participants
Very low

Mood stabilisers vs placebo

Anxiety · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 71 participants
Very low

Mood stabilisers vs placebo

Functional impairment · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Very low

Mood stabilisers vs placebo

Responder status · treatment of disordered and problem gambling

It is very uncertain whether mood stabilisers changes responder status compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
RR 2.69 [1.14, 6.32]
1 study · 40 participants
Very low

Atypical antipsychotics vs placebo

Gambling symptom severity · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 63 participants
Very low

Atypical antipsychotics vs placebo

Gambling expenditure · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Atypical antipsychotics vs placebo

Gambling frequency ‐ not measured · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Atypical antipsychotics vs placebo

Time spent gambling ‐ not measured · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Atypical antipsychotics vs placebo

Depressive symptoms · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Antidepressants vs placebo

Gambling frequency ‐ not measured · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low