Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

24 questions · 24 findings · 2 reviews

No studies found 3 · 12.5%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 4.2%Moderate 18 · 75%High 2 · 8.3%

Oral direct thrombin inhibitors (DTIs) vs conventional anticoagulation

Non‐fatal PE (3 to 12 months) · participants with diagnosed DVT

Oral DTIs showed no clear difference in non‐fatal PE (7 months) compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review

Oral direct thrombin inhibitors (DTIs) vs conventional anticoagulation

All‐cause mortality (7 months) · participants with diagnosed DVT

Oral DTIs showed no clear difference in all‐cause mortality (7 months) compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review