Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

36 questions · 39 findings · 10 reviews

No studies found 9 · 23.1%GRADE not reported 13 · 33.3%Very low 3 · 7.7%Low 5 · 12.8%Moderate 6 · 15.4%High 3 · 7.7%

Morphine via pharmacokinetically based PCA (PKPCA) vs Morphine via patient-controlled analgesia (PCA)

Daily mean opiate intake per hour · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis

Morphine via pharmacokinetically based PCA (PKPCA) led to higher daily mean opiate intake per hour compared with morphine via patient-controlled analgesia (PCA); GRADE not reported.

1 finding from 1 review

Morphine via pharmacokinetically based PCA (PKPCA) vs Morphine via patient-controlled analgesia (PCA)

Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis

Morphine via pharmacokinetically based PCA (PKPCA) led to lower average pain scores (0-100 VAS) compared with morphine via patient-controlled analgesia (PCA); GRADE not reported.

1 finding from 1 review

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs placebo or no treatment

Amount of analgesia · Patients with cancer receiving chemotherapy and/or radiotherapy

The review found no eligible studies for this question.

1 finding from 1 review