Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

53 questions · 55 findings · 12 reviews · Haematology

No studies found 17 · 30.9%GRADE not reported 2 · 3.6%Very low 13 · 23.6%Low 12 · 21.8%Moderate 8 · 14.5%High 3 · 5.5%

Intervention not reported

Number of patients with at least one bleeding episode of any severity · patients with solid tumours without thrombocytopenia before chemotherapy

It is very uncertain whether the intervention changes number of patients with at least one bleeding episode of any severity (very low certainty).

1 finding from 1 review

Intervention not reported

Number of patients with at least one severe/life‐threatening bleeding episode · patients with solid tumours without thrombocytopenia before chemotherapy

It is very uncertain whether the intervention changes number of patients with at least one severe/life‐threatening… (very low certainty).

1 finding from 1 review

Intervention not reported

Number of patients with at least one bleeding episode of any severity · patients with solid tumours with thrombocytopenia during chemotherapy

It is very uncertain whether the intervention changes number of patients with at least one bleeding episode of any severity (very low certainty).

1 finding from 1 review

Pathogen‐reduced platelets vs standard platelets

Number of participants with 'any bleeding' event(s) (WHO grade 1 to 4 or equivalent) ‐ · thrombocytopenia

Pathogen‐reduced platelets may leads to higher number of participants with 'any bleeding' event(s) (WHO grade 1 to… compared with standard platelets (low certainty).

1 finding from 1 review

Pathogen‐reduced platelets vs standard platelets

Number of participants with 'severe' bleeding event(s) (WHO grade ≥ 3 or equivalent) ‐ · thrombocytopenia

Pathogen‐reduced platelets showed no clear difference in number of participants with 'severe' bleeding event(s) (WHO grade ≥… compared with standard platelets (moderate certainty).

1 finding from 1 review