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Evidence found and GRADE certainty

63 questions · 63 findings · 8 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 10 · 15.9%GRADE not reported 12 · 19%Very low 17 · 27%Low 20 · 31.7%Moderate 3 · 4.8%High 1 · 1.6%

Dexrazoxane vs no cardioprotective intervention

Tumour response rate Defined as number of complete responses (i.e. disappearance of active Hodgkin lymphoma (gallium negative, ≥ 70% decrease in the sum of the products of the perpendicular diameters of measurable lesions, and negative bone marrow... · children with cancer receiving anthracyclines

Dexrazoxane showed no clear difference in tumour response rate Defined as number of complete responses (i.e.… compared with no cardioprotective intervention (low certainty).

1 finding from 1 review