Findings

What do systematic reviews say?

74 questions · 74 findings · 10 reviews · Headline outcomes only

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No studies found 30 · 40.5%GRADE not reported 1 · 1.4%Very low 17 · 23%Low 18 · 24.3%Moderate 8 · 10.8%High 0 · 0%

Intervention not reported

Psychological well‐being SF‐36 Mental Component Summary Score 0 to 100, higher scores indicate higher levels of physical well‐being Immediately post‐intervention · Cancer patients with cognitive impairment due to systemic cancer treatment

1 finding from 1 review

Non‐pharmacological interventions for cognitive impairment due to systemic cancer treatment 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 95 participants
Low

Intervention not reported

Psychological well‐being SF‐36 Mental Component Summary Score 0 to 100, higher scores indicate higher levels of physical well‐being Two‐months post‐intervention · Cancer patients with cognitive impairment due to systemic cancer treatment

1 finding from 1 review

Non‐pharmacological interventions for cognitive impairment due to systemic cancer treatment 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 95 participants
Low

NMDA receptor antagonists vs no treatment, placebo, oral sweet solution, or non‐pharmacological intervention

NFCS pain score during the procedure№ of infants: 112(2 RCTs) Score · procedural pain in neonates

1 finding from 1 review

Non‐opioid analgesics for procedural pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

NMDA receptor antagonists vs no treatment, placebo, oral sweet solution, or non‐pharmacological intervention

Pain score assessed up to 10 minutes after the procedure · procedural pain in neonates

The review found no eligible studies for this question.

1 finding from 1 review

Non‐opioid analgesics for procedural pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NMDA receptor antagonists vs no treatment, placebo, oral sweet solution, or non‐pharmacological intervention

Episodes of bradycardia · procedural pain in neonates

The review found no eligible studies for this question.

1 finding from 1 review

Non‐opioid analgesics for procedural pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NMDA receptor antagonists vs no treatment, placebo, oral sweet solution, or non‐pharmacological intervention

Episodes of apnea · procedural pain in neonates

The review found no eligible studies for this question.

1 finding from 1 review

Non‐opioid analgesics for procedural pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NMDA receptor antagonists vs no treatment, placebo, oral sweet solution, or non‐pharmacological intervention

Hypotension requiring medical therapy (vasopressors or fluid boluses), occurring during the procedure · procedural pain in neonates

The review found no eligible studies for this question.

1 finding from 1 review

Non‐opioid analgesics for procedural pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CBT vs non‐pharmacological intervention

ADHD symptom severity: clinician rated · adults with ADHD (available evidence for participants aged between 25 to 53 years old)

1 finding from 1 review

Cognitive‐behavioural interventions for attention deficit hyperactivity disorder (ADHD) in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 97 participants
Low

CBT vs non‐pharmacological intervention

ADHD symptoms: self‐reported Assessed by: various scales · adults with ADHD (available evidence for participants aged between 25 to 53 years old)

1 finding from 1 review

Cognitive‐behavioural interventions for attention deficit hyperactivity disorder (ADHD) in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 156 participants
Low

Non‐nutritive sucking (NNS) vs no intervention

Pain reactivity (first 30 seconds post‐procedure) · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 597 participants
Very low

Facilitated tucking vs no intervention

Pain reactivity (first 30 seconds post‐procedure) · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 733 participants
Very low

Facilitated tucking vs no intervention

Immediate pain regulation (between 30 seconds and 5 minutes post‐procedure) · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 557 participants
Very low

Facilitated tucking vs no intervention

Adverse events · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 299 participants
Very low

Structured parent involvement vs no intervention

Pain reactivity (first 30 seconds post‐procedure) · full‐term born older infants

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 653 participants
Moderate

Structured parent involvement vs no intervention

Immediate pain regulation (between 30 seconds and 5 minutes post‐procedure) · full‐term born older infants

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 728 participants
Low

Structured parent involvement vs no intervention

Adverse events · full‐term born older infants

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 854 participants
Low

Non‐nutritive sucking (NNS) vs no intervention

Immediate pain regulation (between 30 seconds and 5 minutes post‐procedure) · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 379 participants
Very low

Non‐nutritive sucking (NNS) vs no intervention

Adverse events · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 318 participants
Very low

Non‐nutritive sucking (NNS) vs no intervention

Pain reactivity (first 30 seconds post‐procedure) · full‐term born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 545 participants
Very low

Non‐nutritive sucking (NNS) vs no intervention

Immediate pain regulation (between 30 seconds and 5 minutes post‐procedure) · full‐term born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 536 participants
Very low