Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

69 questions · 69 findings · 5 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 1 · 1.4%Very low 23 · 33.3%Low 29 · 42%Moderate 11 · 15.9%High 5 · 7.2%

Antibody (T cell) vs steroids

Graft loss or death with a functioning graft · kidney transplant recipients: first rejection episode

Antibody (T cell) showed no clear difference in graft loss or death with a functioning graft compared with steroid (stratified by antibody type) (low certainty).

1 finding from 1 review

Antibody (T cell) vs steroids

Treatment adverse events: fever, chills, malaise after drug administration · kidney transplant recipients: first rejection episode

It is very uncertain whether antibody (T cell) changes treatment adverse events: fever, chill, or malaise after drug… compared with steroid (stratified by antibody type) (very low certainty).

1 finding from 1 review

Antibody (T cell) + steroid vs steroids

Graft loss or death with a functioning graft · kidney transplant recipients: first rejection episode

It is very uncertain whether antibody (T cell) + steroid changes graft loss or death with a functioning graft compared with steroid alone (very low certainty).

1 finding from 1 review

Interleukin‐2 RA induction vs monoclonal antibody induction

Acute rejection Acute rejection grade 3A or more verified by biopsy · heart transplant recipients

Interleukin‐2 RA induction showed no clear difference in acute rejection Acute rejection grade 3A or more verified by biopsy compared with monoclonal antibody induction (low certainty).

1 finding from 1 review

Interleukin‐2 RA induction vs monoclonal antibody induction

Infection Number of participants diagnosed with infection · heart transplant recipients

Interleukin‐2 RA induction showed no clear difference in infection Number of participants diagnosed with infection compared with monoclonal antibody induction (low certainty).

1 finding from 1 review

Interleukin‐2 RA induction vs monoclonal antibody induction

Post‐transplantation lymphoproliferative disorder Number of participants diagnosed with PTLD · heart transplant recipients

Interleukin‐2 RA induction showed no clear difference in post‐transplantation lymphoproliferative disorder Number of… compared with monoclonal antibody induction (low certainty).

1 finding from 1 review

Muromonab‐CD3 (T cell) vs other antibody (stratified by comparator)

Failure of acute rejection reversal · kidney transplant recipients: first rejection episode

Muromonab‐CD3 (T cell) showed no clear difference in failure of acute rejection reversal compared with other antibody (stratified by comparator) (moderate certainty).

1 finding from 1 review

Muromonab‐CD3 (T cell) vs other antibody (stratified by comparator)

Recurrent rejection · kidney transplant recipients: first rejection episode

Muromonab‐CD3 (T cell) showed no clear difference in recurrent rejection compared with other antibody (stratified by comparator) (moderate certainty).

1 finding from 1 review

Muromonab‐CD3 (T cell) vs other antibody (stratified by comparator)

Treatment adverse events: fever, chills, malaise after drug administration · kidney transplant recipients: first rejection episode

Muromonab‐CD3 (T cell) may leads to higher treatment adverse events: fever, chills, malaise after drug… compared with other antibody (stratified by comparator) (low certainty).

1 finding from 1 review