Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

98 questions · 102 findings · 3 reviews · Haematology

No studies found 39 · 38.2%GRADE not reported 2 · 2%Very low 4 · 3.9%Low 43 · 42.2%Moderate 9 · 8.8%High 5 · 4.9%

Casirivimab/imdevimab vs placebo

Development of clinical COVID‐19 symptoms within 30 days · SARS‐CoV‐2 uninfected people without defined exposure, or with potential exposure to SARS‐CoV‐2

Casirivimab/imdevimab leads to lower development of clinical COVID‐19 symptoms within 30 days compared with placebo (high certainty).

1 finding from 1 review

Casirivimab/imdevimab vs placebo

Serious adverse events until data cut‐offb · SARS‐CoV‐2 uninfected people without defined exposure, or with potential exposure to SARS‐CoV‐2

Casirivimab/imdevimab showed no clear difference in serious adverse events until data cut‐offb compared with placebo (low certainty).

1 finding from 1 review