Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

75 questions · 75 findings · 8 reviews · Headline outcomes only

No studies found 23 · 30.7%GRADE not reported 1 · 1.3%Very low 16 · 21.3%Low 24 · 32%Moderate 11 · 14.7%High 0 · 0%

Summary of findings ‐ Inhaled mannitol vs placebo

Hospitalisations Number of participants experiencing one of more hospitalisations. · people with bronchiectasis

Inhaled mannitol showed no clear difference in hospitalisations Number of participants experiencing one of more… compared with placebo (moderate certainty).

1 finding from 1 review

Summary of findings ‐ Inhaled mannitol vs placebo

SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · people with bronchiectasis

Inhaled mannitol showed no clear difference in health‐related quality of life measured on the SGRQ Scale from 0 to… compared with placebo (moderate certainty).

1 finding from 1 review