Findings

What do systematic reviews say?

77 questions · 79 findings · 25 reviews · Airways

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No studies found 0 · 0%GRADE not reported 3 · 3.8%Very low 8 · 10.1%Low 37 · 46.8%Moderate 20 · 25.3%High 11 · 13.9%

Mepolizumab 100 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 911 participants
Moderate

Mepolizumab 100 mg vs placebo

Change in SGRQ total score · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1285 participants
Moderate

Mucolytic vs placebo

SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · chronic bronchitis or COPD

1 finding from 1 review

Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 2721 participants
Moderate

Group 1 Pulmonary arterial hypertension ‐ PDE5i vs placebo

QoL · pulmonary arterial hypertension

1 finding from 1 review

Phosphodiesterase 5 inhibitors for pulmonary hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 163 participants
GRADE not reported

Selexipag vs placebo

Cardiac index · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Moderate

Selexipag vs placebo

RAP · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Moderate

Selexipag vs placebo

Dyspnea · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Moderate

Prostacyclin vs control

Cardiac index · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 868 participants
Low

Prostacyclin vs control

RAP · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1060 participants
Moderate

Prostacyclin vs control

Dyspnea · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1521 participants
Low

LABA/LAMA vs placebo

SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · Adults with COPD

1 finding from 1 review

Once daily long‐acting beta2‐agonists and long‐acting muscarinic antagonists in a combined inhaler versus placebo for… 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 4952 participants
High

Antibiotics vs placebo or usual care

Symptom score at 10 days. Measured on a 7‐point scale (0 to 6) ; lower score denotes fewer symptoms · acute asthma exacerbation

1 finding from 1 review

Antibiotics for exacerbations of asthma 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
Moderate

Summary of findings for AMBMT vs PR

Units of SGRQ change from baseline · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Active mind‐body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 249 participants
Low

Summary of findings for AMBMT vs PR

CAT score · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Active mind‐body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 74 participants
Low

Summary of findings for AMBMT vs PR

Dyspnoea ‐ change in mMRC Scale 0 to 4. Lower is better and 1 unit is a clinically important difference · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Active mind‐body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with… 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 127 participants
Very low

Summary of findings for AMBMT vs PR

Change in dyspnoea score · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Active mind‐body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 139 participants
Very low

Summary of findings for AMBMT + PR vs PR

Units of SGRQ change from baseline · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Active mind‐body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 192 participants
Moderate

Intervention not reported

Health‐related quality of life (respiratory specific) St George's Respiratory Questionnaire (SGRQ; total score) Scale from 0‐100 Lower value post intervention is favourable, indicating improvement in health‐related quality of life · people with stable COPD

1 finding from 1 review

Singing for adults with chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 58 participants
Low

Intervention not reported

Breathlessness ‐ all trials Lower score indicates improvement in breathlessness · patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy

1 finding from 1 review

Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen… 2016 · Cochrane Headline outcomes only
no estimate extracted
32 studies · 865 participants
Low

Intervention not reported

Breathlessness ‐ subgroup analysis ‐ studies using short‐burst oxygen Lower score indicates improvement in breathlessness · patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy

1 finding from 1 review

Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen… 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 90 participants
Low