Decrease in frequency of attacks · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Levamisole (150 mg per day) showed no clear difference in decrease in frequency of attacks compared with placebo; GRADE not reported.
1 finding from 1 review
RR 4.29 [0.72, 25.39]
1 study
GRADE not reported
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Patients receiving levamisole reported more adverse effects than those receiving placebo (mild stomach upset/nausea, diarrhoea, sleeplessness, dysgeusia/dysosmia), however no adverse effects were reported as requiring…
8 studies
GRADE not reported
Effectiveness · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Decrease in duration of attacks · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Levamisole (150 mg per day) showed no clear difference in decrease in duration of attacks compared with placebo; GRADE not reported.
1 finding from 1 review
RR 4.29 [0.67, 27.24]
1 study
GRADE not reported
Decrease in number of ulcers · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Levamisole (150 mg per day) showed no clear difference in decrease in number of ulcers compared with placebo; GRADE not reported.
1 finding from 1 review
RR 7.88 [0.51, 121.96]
1 study
GRADE not reported
Frequent relapses · SSNS in children
Mycophenolate mofetil showed no clear difference in frequent relapses at 12 months compared with levamisole (low certainty).
1 finding from 1 review
Mean relapse rate/patient/month · SSNS in children
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Peritonitis · SSNS in children
It is very uncertain whether mycophenolate mofetil changes adverse effects: peritonitis compared with levamisole (very low certainty).
1 finding from 1 review
Abdominal pain · SSNS in children
Mycophenolate mofetil showed no clear difference in adverse effects: abdominal pain compared with levamisole (low certainty).
1 finding from 1 review
Adverse effects: anaemia · SSNS in children
It is very uncertain whether mycophenolate mofetil changes adverse effects: anaemia compared with levamisole (very low certainty).
1 finding from 1 review
Adverse effects: leukopenia · SSNS in children
It is very uncertain whether mycophenolate mofetil changes adverse effects: leukopenia compared with levamisole (very low certainty).
1 finding from 1 review
Relapse · SSNS in children
Mycophenolate mofetil showed no clear difference in relapses at 12 months compared with levamisole (low certainty).
1 finding from 1 review