Findings

What do systematic reviews say?

22 questions · 22 findings · 4 reviews

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No studies found 6 · 27.3%GRADE not reported 0 · 0%Very low 4 · 18.2%Low 12 · 54.5%Moderate 0 · 0%High 0 · 0%

NSAIDs vs paracetamol

Little or no swelling on day 7 or later · people with acute soft tissue injury, such as ankle sprain

NSAID showed no clear difference in little or no swelling on day 7 or later compared with paracetamol (low certainty).

1 finding from 1 review

Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes only
RR 0.84 [0.58, 1.22]
1 study · 77 participants
Low

NSAIDs vs paracetamol

Return to function on day 7 or later (numbers returning to full function or returning to training) · people with acute soft tissue injury, such as ankle sprain

It is very uncertain whether NSAID changes return to function on day 7 or latere compared with paracetamol (very low certainty).

1 finding from 1 review

Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes only
RR 0.99 [0.9, 1.09]
3 studies · 386 participants
Very low