Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

578 questions · 600 findings · 55 reviews · Headline outcomes only

No studies found 143 · 23.8%GRADE not reported 69 · 11.5%Very low 100 · 16.7%Low 142 · 23.7%Moderate 116 · 19.3%High 30 · 5%

Intermittent LTRA vs placebo

Number of participants experiencing one or more episode requiring treatment with oral steroids · episodic viral wheeze in children

Intermittent LTRA showed no clear difference in number of participants experiencing one or more episode requiring… compared with placebo (moderate certainty).

1 finding from 1 review

Intermittent LTRA vs placebo

Number of participants experiencing one or more episodes requiring ED visit · episodic viral wheeze in children

Intermittent LTRA showed no clear difference in number of participants experiencing one or more episodes requiring… compared with placebo (moderate certainty).

1 finding from 1 review

Intermittent LTRA vs placebo

Number of participants experiencing one or more episodes requiring hospital admission · episodic viral wheeze in children

Intermittent LTRA showed no clear difference in number of participants experiencing one or more episodes requiring… compared with placebo (moderate certainty).

1 finding from 1 review