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What do systematic reviews say?

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Evidence found and GRADE certainty

22 questions · 31 findings · 6 reviews · asked by two or more reviews

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No studies found 3 · 9.7%GRADE not reported 0 · 0%Very low 8 · 25.8%Low 12 · 38.7%Moderate 8 · 25.8%High 0 · 0%

Metformin combined with clomiphene citrate vs clomiphene

Gastrointestinal adverse events · women with polycystic ovary syndrome

Metformin combined with clomiphene citrate probably leads to higher adverse events (gastrointestinal) per woman compared with clomiphene citrate alone (moderate certainty).

1 finding from 1 review · compare the 2 reviews

Metformin combined with clomiphene citrate vs clomiphene

Clinical pregnancy rate · women with polycystic ovary syndrome

Metformin combined with clomiphene citrate probably leads to higher clinical pregnancy rate per woman compared with clomiphene citrate alone (moderate certainty).

1 finding from 1 review · compare the 2 reviews