Findings

What do systematic reviews say?

22 questions · 22 findings · 5 reviews · Schizophrenia

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No studies found 2 · 9.1%GRADE not reported 1 · 4.5%Very low 8 · 36.4%Low 7 · 31.8%Moderate 3 · 13.6%High 1 · 4.5%

Paliperidone palmitate vs risperidone long‐acting injection

Leaving the study early · patients with schizophrenia

Paliperidone palmitate showed no clear difference in leaving the study early ‐ any reason Reported by trial author compared with risperidone long‐acting injection (high certainty).

1 finding from 1 review

Paliperidone palmitate for schizophrenia 2012 · Cochrane Headline outcomes only
RR 1.12 [1, 1.25]
2 studies · 1969 participants
High

Paliperidone palmitate vs risperidone long‐acting injection

Leaving the study early ‐ lack of efficacy Reported by trial author · patients with schizophrenia

Paliperidone palmitate probably leads to higher leaving the study early ‐ lack of efficacy Reported by trial author compared with risperidone long‐acting injection (moderate certainty).

1 finding from 1 review

Paliperidone palmitate for schizophrenia 2012 · Cochrane Headline outcomes only
RR 1.35 [1.06, 1.71]
2 studies · 1969 participants
Moderate