Findings

What do systematic reviews say?

25 questions · 25 findings · 2 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

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No studies found 6 · 24%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 16%Moderate 5 · 20%High 10 · 40%

Hyperbaric oxygen vs control without HBOT

Visual disturbances · any person with radiation tissue injury arising later than 6 months after irradiation (LRTI), including dysfunction or necrosis of any…

Hyperbaric oxygen therapy (HBOT) leads to higher visual disturbances compared with control without HBOT (high certainty).

1 finding from 1 review

Hyperbaric oxygen therapy for late radiation tissue injury 2023 · Cochrane Headline outcomes only
RR 4.03 [1.65, 9.84]
5 studies · 438 participants
High

Hyperbaric oxygen vs control without HBOT

Otic barotrauma · any person with radiation tissue injury arising later than 6 months after irradiation (LRTI), including dysfunction or necrosis of any…

Hyperbaric oxygen therapy (HBOT) leads to higher otic barotrauma compared with control without HBOT (high certainty).

1 finding from 1 review

Hyperbaric oxygen therapy for late radiation tissue injury 2023 · Cochrane Headline outcomes only
RR 9.08 [2.21, 37.26]
4 studies · 357 participants
High

Hyperbaric oxygen vs control without HBOT

Wound dehiscence · any person with osteoradionecrosis of the jaw or at risk of osteoradionecrosis of the jaw

Hyperbaric oxygen therapy (HBOT) may leads to lower wound dehiscence compared with control without HBOT (low certainty).

1 finding from 1 review

Hyperbaric oxygen therapy for late radiation tissue injury 2023 · Cochrane Headline outcomes only
RR 0.24 [0.06, 0.94]
2 studies · 264 participants
Low

Hyperbaric oxygen vs control without HBOT

Pain score change at 12 months · any person with osteoradionecrosis of the jaw or at risk of osteoradionecrosis of the jaw

1 finding from 1 review

Hyperbaric oxygen therapy for late radiation tissue injury 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 157 participants
Moderate

Hyperbaric oxygen vs control without HBOT

Complete resolution or significant improvement of osteoradionecrosis · any person with osteoradionecrosis of the jaw or at risk of osteoradionecrosis of the jaw

Hyperbaric oxygen therapy (HBOT) showed no clear difference in complete resolution or significant improvement of osteoradionecrosis compared with control without HBOT (low certainty).

1 finding from 1 review

Hyperbaric oxygen therapy for late radiation tissue injury 2023 · Cochrane Headline outcomes only
RR 1.26 [0.87, 1.82]
3 studies · 239 participants
Low