OHSS · Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only showed no clear difference in OHSS rate (mild, moderate or severe) per woman compared with monitoring with TVUS plus serum estradiol (low certainty).
1 finding from 1 review
Cancellation rate per woman · Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only showed no clear difference in cycle cancellation rate per woman compared with monitoring with TVUS plus serum estradiol (low certainty).
1 finding from 1 review
Ongoing pregnancy / live birth rate per woman · patients with ovarian stimulation in assisted reproductive technology cycles
rFSH showed no clear difference in live birth (or ongoing pregnancy) by urinary gonadotrophin compared with urinary gonadotrophins: primary analyses (high certainty).
4 findings from 1 review
OR 0.97 [0.87, 1.08]
28 studies · 7339 participants
High
OR 0.84 [0.72, 0.99]
11 studies · 3197 participants
High
OR 1.26 [0.96, 1.64]
5 studies · 1430 participants
High
Show 1 more finding
OHSS by urinary gonadotrophin · patients with ovarian stimulation in assisted reproductive technology cycles
rFSH showed no clear difference in OHSS by urinary gonadotrophin compared with urinary gonadotrophins: primary analyses (high certainty).
1 finding from 1 review
OHSS · ovulation induction in polycystic ovarian syndrome
It is very uncertain whether human menopausal gonadotrophin or highly purified human menopausal… changes incidence of OHSS per woman compared with urinary follicle stimulating hormone (very low certainty).
1 finding from 1 review
Live birth rate per woman · ovulation induction in polycystic ovarian syndrome
It is very uncertain whether human menopausal gonadotrophin or highly purified human menopausal… changes live birth rate per woman compared with urinary follicle stimulating hormone (very low certainty).
1 finding from 1 review
Multiple pregnancy rate · ovulation induction in polycystic ovarian syndrome
It is very uncertain whether human menopausal gonadotrophin or highly purified human menopausal… changes incidence of multiple pregnancy (per woman) compared with urinary follicle stimulating hormone (very low certainty).
1 finding from 1 review
Clinical pregnancy rate · ovulation induction in polycystic ovarian syndrome
It is very uncertain whether human menopausal gonadotrophin or highly purified human menopausal… changes clinical pregnancy rate per woman compared with urinary follicle stimulating hormone (very low certainty).
1 finding from 1 review
Miscarriage · ovulation induction in polycystic ovarian syndrome
It is very uncertain whether human menopausal gonadotrophin or highly purified human menopausal… changes miscarriage rate per woman compared with urinary follicle stimulating hormone (very low certainty).
1 finding from 1 review
Live birth rate per woman · women with polycystic ovary syndrome
Metformin showed no clear difference in live birth rate per woman compared with placebo or no treatment (low certainty).
1 finding from 1 review
Miscarriage · women with polycystic ovary syndrome
Metformin combined with clomiphene citrate showed no clear difference in miscarriage rate per woman compared with clomiphene citrate alone (low certainty).
Live birth rate per woman aParticipants with BMI < 30 kg/m2 or ≤ 32 kg/m2 · women with polycystic ovary syndrome
It is very uncertain whether metformin changes live birth rate per woman aParticipants with BMI < 30 kg/m2 or ≤ 32… compared with clomiphene citrate (very low certainty).
Live birth rate per woman aParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome
It is very uncertain whether metformin changes live birth rate per woman aParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (very low certainty).
Gastrointestinal adverse events · women with polycystic ovary syndrome
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
Clinical pregnancy rate per woman Participants with BMI < 30 kg/m2 or ≤ 32 kg/m2a · women with polycystic ovary syndrome
Metformin may leads to higher clinical pregnancy rate per womanaParticipants with BMI < 30 kg/m2… compared with clomiphene citrate (low certainty).
Clinical pregnancy rate per woman aParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome
Metformin may leads to lower clinical pregnancy rate per woman aParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (low certainty).
Ovulation rate per woman fParticipants with BMI < 30 kg/m2 · women with polycystic ovary syndrome
Metformin showed no clear difference in ovulation rate per woman fParticipants with BMI < 30 kg/m2 compared with clomiphene citrate (low certainty).
Ovulation rate per woman fParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome
Metformin may leads to lower ovulation rate per woman fParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (low certainty).
Miscarriage rate per woman aParticipants with BMI < 30 kg/2 · women with polycystic ovary syndrome
Metformin showed no clear difference in miscarriage rate per woman aParticipants with BMI < 30 kg/2 compared with clomiphene citrate (low certainty).
1 finding from 1 review
Miscarriage rate per woman aParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome
Metformin showed no clear difference in miscarriage rate per woman aParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (low certainty).
1 finding from 1 review