Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

45 questions · 46 findings · 9 reviews

No studies found 10 · 21.7%GRADE not reported 4 · 8.7%Very low 18 · 39.1%Low 5 · 10.9%Moderate 7 · 15.2%High 2 · 4.3%

Glutamine vs placebo

Incidence of hepatic veno‐occlusive disease ( · People undergoing stem cell transplant with haematological malignancies

It is very uncertain whether summary of findings: Glutamine changes incidence of hepatic veno‐occlusive disease ( compared with placebo (very low certainty).

1 finding from 1 review

Glutamine vs placebo

All‐cause mortality at 100 days post‐transplant · People undergoing stem cell transplant with haematological malignancies

It is very uncertain whether summary of findings: Glutamine changes all‐cause mortality at 100 days post‐transplant ( compared with placebo (very low certainty).

1 finding from 1 review

Glutamine vs placebo

Mortality attributable to hepatic veno‐occlusive disease ( · People undergoing stem cell transplant with haematological malignancies

It is very uncertain whether summary of findings: Glutamine changes mortality attributable to hepatic veno‐occlusive disease ( compared with placebo (very low certainty).

1 finding from 1 review

Arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement vs placebo

Development of any new foot ulcers · people with diabetes and foot ulcers

It is very uncertain whether arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement changes development of any new foot ulcers compared with placebo (very low certainty).

1 finding from 1 review

Arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement vs placebo

Ulcer healing · people with diabetes and foot ulcers

The review found no eligible studies for this question.

2 findings from 1 review

Enteral nutrition via nasojejunal tube plus intravenous glutamine‐dipeptide supplementation vs parenteral nutrition

All‐cause mortality during hospital stay · adult patients after liver transplantation.

It is very uncertain whether enteral nutrition via nasojejunal tube plus intravenous… changes death (during length of initial hospital stay; ITT) compared with standard parenteral nutrition (very low certainty).

1 finding from 1 review

Enteral nutrition via nasojejunal tube plus intravenous glutamine‐dipeptide supplementation vs parenteral nutrition

Infection (ITT) ‐ mycotic infection · adult patients after liver transplantation.

It is very uncertain whether enteral nutrition via nasojejunal tube plus intravenous… changes infection (ITT) ‐ mycotic infection compared with standard parenteral nutrition (very low certainty).

1 finding from 1 review

Enteral nutrition via nasojejunal tube plus intravenous glutamine‐dipeptide supplementation vs parenteral nutrition

Infection (ITT) ‐ infection (overall) · adult patients after liver transplantation.

It is very uncertain whether enteral nutrition via nasojejunal tube plus intravenous… changes infection (ITT) ‐ infection (overall) compared with standard parenteral nutrition (very low certainty).

1 finding from 1 review

Enteral nutrition via nasojejunal tube plus intravenous glutamine‐dipeptide supplementation vs parenteral nutrition

Acute rejection · adult patients after liver transplantation.

It is very uncertain whether enteral nutrition via nasojejunal tube plus intravenous… changes acute rejection (ITT) compared with standard parenteral nutrition (very low certainty).

1 finding from 1 review

Parenteral nutrition with alanyl‐glutamine, protein, fat, carbohydrates and branched‐chain amino acids vs 5% dextrose and normal saline

1‐year‐survival · adult patients after liver transplantation.

It is very uncertain whether parenteral nutrition with alanyl‐glutamine, protein, fat,… changes 1‐year‐survival compared with 5% dextrose and normal saline (very low certainty).

1 finding from 1 review

Parenteral nutrition with alanyl‐glutamine, protein, fat, carbohydrates and branched‐chain amino acids vs 5% dextrose and normal saline

3‐year‐survival · adult patients after liver transplantation.

It is very uncertain whether parenteral nutrition with alanyl‐glutamine, protein, fat,… changes 3‐year‐survival compared with 5% dextrose and normal saline (very low certainty).

1 finding from 1 review