Findings

What do systematic reviews say?

42 questions · 42 findings · 3 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 22 · 52.4%Low 12 · 28.6%Moderate 2 · 4.8%High 6 · 14.3%

Highest vs lowest green tea exposure

Prostate cancer risk (13 studies) · adults (aged at least 18 years)

It is very uncertain whether highest changes prostate cancer risk (13 studies) compared with lowest green tea exposure (very low certainty).

1 finding from 1 review

Green tea (Camellia sinensis) for the prevention of cancer 2020 · Cochrane Headline outcomes only
RR 0.73 [0.56, 0.94]
127239 participants
Very low

Highest vs lowest green tea exposure

Urinary tract cancer risk (7 studies) · adults (aged at least 18 years)

It is very uncertain whether highest changes urinary tract cancer risk (7 studies) compared with lowest green tea exposure (very low certainty).

1 finding from 1 review

Green tea (Camellia sinensis) for the prevention of cancer 2020 · Cochrane Headline outcomes only
RR 1.04 [0.79, 1.37]
156039 participants
Very low

Highest vs lowest green tea exposure

Incidence: all cancers · adults (aged at least 18 years)

Highest showed no clear difference in any cancer incidence (3 studies) compared with lowest green tea exposure (low certainty).

1 finding from 1 review

Green tea (Camellia sinensis) for the prevention of cancer 2020 · Cochrane Headline outcomes only
RR 0.83 [0.65, 1.07]
52479 participants
Low

Highest vs lowest green tea exposure

Mortality: all cancers · adults (aged at least 18 years)

Highest showed no clear difference in any cancer mortality (8 studies) compared with lowest green tea exposure (low certainty).

1 finding from 1 review

Green tea (Camellia sinensis) for the prevention of cancer 2020 · Cochrane Headline outcomes only
RR 0.99 [0.91, 1.07]
504366 participants
Low

Highest vs lowest green tea exposure

Oral cancer risk · adults (aged at least 18 years)

Highest may leads to lower oral cancer risk (5 studies) compared with lowest green tea exposure (low certainty).

1 finding from 1 review

Green tea (Camellia sinensis) for the prevention of cancer 2020 · Cochrane Headline outcomes only
RR 0.71
55977 participants
Low

Highest vs lowest green tea exposure

Any gut cancer risk (7 studies) · adults (aged at least 18 years)

Highest showed no clear difference in any gut cancer risk (7 studies) compared with lowest green tea exposure (low certainty).

1 finding from 1 review

Green tea (Camellia sinensis) for the prevention of cancer 2020 · Cochrane Headline outcomes only
RR 0.78 [0.59, 1.02]
70299 participants
Low

Highest vs lowest green tea exposure

Oesophageal cancer risk (13 studies) · adults (aged at least 18 years)

It is very uncertain whether highest changes oesophageal cancer risk (13 studies) compared with lowest green tea exposure (very low certainty).

1 finding from 1 review

Green tea (Camellia sinensis) for the prevention of cancer 2020 · Cochrane Headline outcomes only
RR 0.81 [0.64, 1.04]
74895 participants
Very low

Highest vs lowest selenium exposure

Any cancer risk No. of participants: 19,475 (3 RCTs) · Participants in trials with low risk of bias

Highest showed no clear difference in any cancer risk No. of participants: 19,475 (3 RCTs) compared with lowest selenium exposure (high certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
RR 1.01 [0.93, 1.1]
Studies not reported
High

Highest vs lowest selenium exposure

Mortality: all cancers · Participants in non experimental cohort studies on selenium and cancer

It is very uncertain whether highest changes cancer mortality risk No. of participants: 183,863 (7 observational… compared with lowest selenium exposure (very low certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
OR 0.76 [0.59, 0.97]
Studies not reported
Very low

Highest vs lowest selenium exposure

Colorectal cancer risk (16 studies) · Participants in non experimental cohort studies on selenium and cancer

It is very uncertain whether highest changes colorectal cancer risk No. of participants: 712,746 (6 observational… compared with lowest selenium exposure (very low certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
OR 0.82 [0.72, 0.94]
Studies not reported
Very low

Highest vs lowest selenium exposure

Lung cancer risk (17 studies) · Participants in non experimental cohort studies on selenium and cancer

It is very uncertain whether highest changes lung cancer risk No. of participants: 371,067 (11 observational… compared with lowest selenium exposure (very low certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
OR 0.82 [0.59, 1.14]
Studies not reported
Very low

Highest vs lowest selenium exposure

Breast cancer risk (14 studies) · Participants in non experimental cohort studies on selenium and cancer

It is very uncertain whether highest changes breast cancer risk (women) No. of participants: 169,028 (8… compared with lowest selenium exposure (very low certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
OR 1.09 [0.87, 1.37]
Studies not reported
Very low

Highest vs lowest selenium exposure

Bladder cancer risk No. of participants: 279,100 (5 observational studies) · Participants in non experimental cohort studies on selenium and cancer

It is very uncertain whether highest changes bladder cancer risk No. of participants: 279,100 (5 observational… compared with lowest selenium exposure (very low certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
OR 0.67 [0.46, 0.97]
Studies not reported
Very low

Highest vs lowest selenium exposure

Prostate cancer risk (13 studies) · Participants in non experimental cohort studies on selenium and cancer

It is very uncertain whether highest changes prostate cancer risk No. of participants: 576,667 (21 observational… compared with lowest selenium exposure (very low certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
OR 0.84 [0.75, 0.95]
Studies not reported
Very low

Highest vs lowest selenium exposure

Cancer mortality risk No. of participants: 17,448 (1 RCT) · Participants in trials with low risk of bias

Highest showed no clear difference in cancer mortality risk No. of participants: 17,448 (1 RCT) compared with lowest selenium exposure (high certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
RR 1.02 [0.8, 1.3]
Studies not reported
High

Highest vs lowest selenium exposure

Colorectal cancer risk (16 studies) · Participants in trials with low risk of bias

Highest showed no clear difference in colorectal cancer risk No. of participants: 19,009 (2 RCTs) compared with lowest selenium exposure (high certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
RR 0.99 [0.69, 1.43]
Studies not reported
High

Highest vs lowest selenium exposure

Non‐melanoma skin cancer risk No. of participants: 2027 (2 RCTs) · Participants in trials with low risk of bias

Highest showed no clear difference in non‐melanoma skin cancer risk No. of participants: 2027 (2 RCTs) compared with lowest selenium exposure (moderate certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
RR 1.16 [0.3, 4.42]
Studies not reported
Moderate

Highest vs lowest selenium exposure

Lung cancer risk (17 studies) · Participants in trials with low risk of bias

Highest showed no clear difference in lung cancer risk No. of participants: 19,009 (2 RCTs) compared with lowest selenium exposure (high certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
RR 1.16 [0.89, 1.5]
Studies not reported
High

Highest vs lowest selenium exposure

Breast cancer risk (14 studies) · Participants in trials with low risk of bias

Highest showed no clear difference in breast cancer risk No. of participants: 802 (1 RCT) compared with lowest selenium exposure (moderate certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
RR 2.04 [0.44, 9.55]
Studies not reported
Moderate

Highest vs lowest selenium exposure

Bladder cancer risk No. of participants: 19,009 (2 RCTs) · Participants in trials with low risk of bias

Highest showed no clear difference in bladder cancer risk No. of participants: 19,009 (2 RCTs) compared with lowest selenium exposure (high certainty).

1 finding from 1 review

Selenium for preventing cancer 2018 · Cochrane Headline outcomes only
RR 1.07 [0.76, 1.52]
Studies not reported
High