Taxane‐containing chemotherapy vs any chemotherapy without taxane
Quality of life · women with early breast cancer
1 finding from 1 review
- no estimate extracted7 studies · 7 participantsLow
Findings
What do systematic reviews say?
24 questions · 24 findings · 6 reviews · Breast Cancer
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 6 · 25%Low 6 · 25%Moderate 7 · 29.2%High 5 · 20.8%
Taxane‐containing chemotherapy vs any chemotherapy without taxane
Febrile neutropenia · women with early breast cancer
Taxane‐containing chemotherapy showed no clear difference in febrile neutropenia compared with any chemotherapy without taxane (moderate certainty).
1 finding from 1 review
- OR 1.43 [0.89, 2.31]23 studies · 34154 participantsModerate
Taxane‐containing chemotherapy vs any chemotherapy without taxane
Neuropathy (including grade 3/4 sensory or motor neuropathy, or both) · women with early breast cancer
Taxane‐containing chemotherapy probably leads to higher neuropathy (including grade 3/4 sensory or motor neuropathy, or both) compared with any chemotherapy without taxane (moderate certainty).
1 finding from 1 review
- OR 6.89 [3.23, 14.71]22 studies · 31033 participantsModerate
Taxane‐containing chemotherapy vs any chemotherapy without taxane
Cardiotoxicity (including grade 3/4 and congestive cardiac failure) · women with early breast cancer
Taxane‐containing chemotherapy showed no clear difference in cardiotoxicity (including grade 3/4 and congestive cardiac failure) compared with any chemotherapy without taxane (moderate certainty).
1 finding from 1 review
- OR 0.87 [0.56, 1.33]23 studies · 32894 participantsModerate