Adverse effects: 1. Sedation · Adults (aged 18 and over) with acute mania
Valproate showed no clear difference in individual adverse events ‐ Sedation At 3 weeks (secondary… compared with lithium (low certainty).
1 finding from 1 review
Adverse events: somnolence/sedation · Children and adolescents with acute mania
It is very uncertain whether valproate changes individual adverse events ‐ Sedation At 8 weeks (secondary… compared with lithium (very low certainty).
1 finding from 1 review
Adverse effects: 1. Sedation · Adults (aged 18 and over) with acute mania
Valproate showed no clear difference in individual adverse events ‐ Sedation At 3‐8 weeks (secondary… compared with placebo (high certainty).
1 finding from 1 review
Adverse effects: 1. Sedation · Children and adolescents with acute mania
It is very uncertain whether valproate changes individual adverse events ‐ Sedation At 4 weeks (secondary… compared with placebo (very low certainty).
1 finding from 1 review
Intervention not reported
Response rate at post‐treatment (as defined in individual studies) · women with postnatal depression
It is very uncertain whether the intervention changes response rate at post‐treatment (as defined in individual studies) (very low certainty).
1 finding from 1 review
Intervention not reported
Remission rate at post‐treatment (as defined in individual studies) · women with postnatal depression
It is very uncertain whether the intervention changes remission rate at post‐treatment (as defined in individual studies) (very low certainty).
1 finding from 1 review
Outcomes · obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment efficacy (change in OCD score), end of treatment. Measured by Y‐BOCs Score · obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)
1 finding from 1 review
Dropout · obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)
Cognitive behavioural therapy showed no clear difference in total number of dropouts, end of treatment compared with anxiety management (low certainty).
1 finding from 1 review
Quality of life, end of treatment Measured by WSAS Score · obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)
1 finding from 1 review
Depressive symptoms · obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)
1 finding from 1 review
Severity of anxiety symptoms, end of treatment Measured by BDI Score · obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)
1 finding from 1 review
Behavioural difficulties, end of treatment · obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Severity of PTSD symptoms · post‐traumatic stress disorder (PTSD)
1 finding from 1 review
Dyadic adjustment · post‐traumatic stress disorder (PTSD)
1 finding from 1 review
Family member severity of depression · post‐traumatic stress disorder (PTSD)
1 finding from 1 review
Family member severity of anxiety · post‐traumatic stress disorder (PTSD)
1 finding from 1 review
Severity of depression · post‐traumatic stress disorder (PTSD)
1 finding from 1 review
Anxiety · post‐traumatic stress disorder (PTSD)
1 finding from 1 review
Family functioning · post‐traumatic stress disorder (PTSD)
1 finding from 1 review