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What do systematic reviews say?

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Evidence found and GRADE certainty

23 questions · 23 findings · 5 reviews · Common Mental Disorders

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No studies found 7 · 30.4%GRADE not reported 0 · 0%Very low 3 · 13%Low 9 · 39.1%Moderate 3 · 13%High 1 · 4.3%

COMPARISON 1. ARIPIPRAZOLE vs other drugs

≥ 50% decrease in total YMRS from baseline at three weeks Young Mania Rating Scale (as above) · patients with an acute manic or mixed episode

Aripiprazole showed no clear difference in ≥ 50% decrease in YMRS from baseline at week three Young Mania… compared with other drug treatment (moderate certainty).

1 finding from 1 review

COMPARISON 1. ARIPIPRAZOLE vs other drugs

Numbers completing the trial (at end of week three) Number of participants · patients with an acute manic or mixed episode

Aripiprazole may leads to higher numbers completing the trial (at end of week three) Number of… compared with other drug treatment (low certainty).

1 finding from 1 review