Findings

What do systematic reviews say?

27 questions · 29 findings · 4 reviews · Headline outcomes only

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No studies found 2 · 6.9%GRADE not reported 2 · 6.9%Very low 8 · 27.6%Low 14 · 48.3%Moderate 3 · 10.3%High 0 · 0%

Children: prednisolone vs dexamethasone

Admission to hospital at initial presentation · children with acute asthma

Children: prednisolone showed no clear difference in admission at initial presentation compared with dexamethasone (low certainty).

1 finding from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 1.08 [0.74, 1.58]
3 studies · 1007 participants
Low

Children: prednisolone vs dexamethasone

Re‐admission during · children with acute asthma

Children: prednisolone showed no clear difference in re‐admission during compared with dexamethasone (low certainty).

1 finding from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 0.44 [0.15, 1.33]
3 studies · 985 participants
Low

Children: prednisolone vs dexamethasone

Asthma symptoms · children with acute asthma

2 findings from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 328 participants
Very low
Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 533 participants
GRADE not reported

Children: prednisolone vs dexamethasone

Serious adverse events · children with acute asthma

1 finding from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 255 participants
GRADE not reported

Children: prednisolone vs dexamethasone

Exacerbations · children with acute asthma

Children: prednisolone showed no clear difference in new exacerbation during compared with dexamethasone (low certainty).

1 finding from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 0.85 [0.54, 1.34]
4 studies · 981 participants
Low

Adults: prednisolone vs dexamethasone

Re‐admission during · Adults with acute asthma

It is very uncertain whether adults: prednisolone changes re‐admission during compared with dexamethasone (very low certainty).

1 finding from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 0.35 [0.04, 3.47]
1 study · 200 participants
Very low

Adults: prednisolone vs dexamethasone

Asthma symptoms Returned to normal activities within 3 days · Adults with acute asthma

Adults: prednisolone showed no clear difference in asthma symptoms Returned to normal activities within 3 days compared with dexamethasone (low certainty).

1 finding from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 0.44 [0.19, 1.01]
1 study · 191 participants
Low