Intervention not reported
Adverse events · adults with IQ >70 with refractory focal epilepsy
1 finding from 1 review
- no estimate extracted1 study · 4 participantsLow
Findings
What do systematic reviews say?
36 questions · 36 findings · 1 reviews · Epilepsy
No studies found 0 · 0%GRADE not reported 1 · 2.8%Very low 8 · 22.2%Low 12 · 33.3%Moderate 10 · 27.8%High 5 · 13.9%
Intervention not reported
Neuropsychological outcome (3 months) · adults with IQ >70 with refractory focal epilepsy
1 finding from 1 review
- no estimate extracted1 study · 4 participantsLow
Intervention not reported
Seizure frequency reduction (%) (3‐month blinded evaluation period) · adults with IQ > 70 with refractory focal epilepsy
1 finding from 1 review
- no estimate extracted1 study · 108 participantsHigh
Intervention not reported
Quality of Life (QOLIE‐31‐P) (3 months) · adults with IQ >70 with refractory focal epilepsy
1 finding from 1 review
- no estimate extracted1 study · 4 participantsLow
Intervention not reported
Seizure freedom (3‐month blinded evaluation period) · adults with refractory focal epilepsy (1 or 2 epileptogenic regions)
The intervention showed no clear difference in seizure freedom (3‐month blinded evaluation period) (moderate certainty).
1 finding from 1 review
- OR 4.95 [0.23, 104.44]1 study · 191 participantsModerate
Intervention not reported
Responder rate (3‐month blinded evaluation period) · adults with refractory focal epilepsy (1 or 2 epileptogenic regions)
The intervention showed no clear difference in responder rate (3‐month blinded evaluation period) (moderate certainty).
1 finding from 1 review
- OR 1.12 [0.59, 2.11]1 study · 191 participantsModerate
Intervention not reported
Seizure frequency reduction (3‐month blinded evaluation period) · adults with refractory focal epilepsy (1 or 2 epileptogenic regions)
1 finding from 1 review
- no estimate extracted1 study · 191 participantsHigh
Intervention not reported
Adverse events · adults with refractory focal epilepsy (1 or 2 epileptogenic regions)
1 finding from 1 review
- no estimate extracted1 study · 191 participantsModerate
Intervention not reported
Neuropsychological outcome (3 months) · adults with refractory focal epilepsy (1 or 2 epileptogenic regions)
1 finding from 1 review
- no estimate extracted1 study · 160 participantsHigh
Intervention not reported
Quality of life (QOLIE‐89) (3 months) · adults with refractory focal epilepsy (1 or 2 epileptogenic regions)
1 finding from 1 review
- no estimate extracted1 study · 180 participantsHigh
Intervention not reported
Adverse events · adults with IQ > 70 with refractory focal epilepsy
1 finding from 1 review
- no estimate extracted1 study · 109 participantsModerate
Intervention not reported
Neuropsychological outcome (3 months) · adults with IQ > 70 with refractory focal epilepsy
1 finding from 1 review
- no estimate extracted1 study · 96 participantsModerate
Intervention not reported
Quality of life (QOLIE‐31) (3 months) · adults with IQ > 70 with refractory focal epilepsy
1 finding from 1 review
- no estimate extracted1 study · 105 participantsHigh
Intervention not reported
Seizure freedom (3‐month blinded evaluation period) · patients with refractory (multi)focal or generalized epilepsy
It is very uncertain whether the intervention changes seizure freedom (3‐month blinded evaluation period) (very low certainty).
1 finding from 1 review
- OR 1 [0.11, 9.39]1 study · 6 participantsVery low
Intervention not reported
Responder rate (3‐month blinded evaluation period) · patients with refractory (multi)focal or generalized epilepsy
It is very uncertain whether the intervention changes responder rate (3‐month blinded evaluation period) (very low certainty).
1 finding from 1 review
- OR 1 [0.27, 3.69]1 study · 6 participantsVery low
Intervention not reported
Seizure frequency reduction (3‐month blinded evaluation period) · patients with refractory (multi)focal or generalized epilepsy
1 finding from 1 review
- no estimate extracted1 study · 6 participantsVery low