Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

90 questions · 90 findings · 23 reviews · Cystic Fibrosis and Genetic Disorders

No studies found 39 · 43.3%GRADE not reported 0 · 0%Very low 22 · 24.4%Low 22 · 24.4%Moderate 5 · 5.6%High 2 · 2.2%

Inhaled tobramycin (TNS) (28 days) vs TNS (56 days)

Frequency of infective pulmonary exacerbations: number of exacerbations per patient year · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

It is very uncertain whether inhaled tobramycin (TNS) (28 days) changes frequency of infective pulmonary exacerbations: number of… compared with TNS (56 days) (very low certainty).

1 finding from 1 review

Inhaled tobramycin (TNS) (28 days) vs TNS (56 days)

Isolation of other micro‐organisms from the respiratory tract: number of positive cultures per patient year · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
1 finding from 1 review

Inhaled tobramycin (TNS) (28 days) vs TNS (56 days)

Eradication of P aeruginosa from the respiratory tract: time to next isolation of P aeruginosa from BAL, sputum or oropharyngeal cultures · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

The review found no eligible studies for this question.

1 finding from 1 review