What do systematic reviews say?

Low‐level laser therapy vs Conventional orthodontic appliance treatment

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
  Abellan 2021 assessed periodontal health (plaque index, pocket depth, bleeding on probing) after intrusion of maxillary molars; no evidence of significant difference with LLLT. Statistical test results not published.
  1 study
  GRADE not reported

Low‐level laser therapy vs Conventional orthodontic appliance treatment

It is very uncertain whether low level laser therapy (LLLT) changes total number of orthodontic appliance adjustment appointments during… compared with conventional orthodontic appliance treatment (very low certainty).

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes

  Alignment stage
  MD -2.25 [-2.52, -1.97]
  2 studies · 125 participants
  Very low

Low‐level laser therapy vs Conventional orthodontic appliance treatment

It is very uncertain whether low level laser therapy (LLLT) changes patient perception of pain and discomfort (VAS 0 to 100 mm) compared with conventional orthodontic appliance treatment (very low certainty).

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes

  Space closure / first visit
  MD -0.4 [-1.87, 1.07]
  1 study · 37 participants
  Very low

Low‐level laser therapy vs Conventional orthodontic appliance treatment

It is very uncertain whether low level laser therapy (LLLT) changes duration of orthodontic treatment during alignment stage compared with conventional orthodontic appliance treatment (very low certainty).

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes

  Alignment stage
  MD -48.87 [-56.48, -41.26]
  3 studies · 92 participants
  Very low

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Light vibrational forces (LVF) showed no clear difference in harms and side effects: orthodontically-induced inflammatory root… compared with conventional orthodontic appliance treatment (placebo or no adjunct) (low certainty).

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
  MD 0.09 [-0.35, 0.53]
  1 study · 50 participants
  Low

Low‐level laser therapy vs Conventional orthodontic appliance treatment

The review found no eligible studies for this question.

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
  Patient-reported need for analgesics | Not reported
  Studies not reported
  No studies found

Low‐level laser therapy vs Conventional orthodontic appliance treatment

The review found no eligible studies for this question.

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
  No study reported on the influence of LLLT on the total number of orthodontic appliance adjustment visits to complete a course of treatment.
  Studies not reported
  No studies found

Low‐level laser therapy vs Conventional orthodontic appliance treatment

The review found no eligible studies for this question.

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
  No study reported on the influence of LLLT on the total overall orthodontic treatment duration.
  Studies not reported
  No studies found

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

The review found no eligible studies for this question.

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
  Orthodontic tooth movement (OTM) during alignment stage | Not reported
  Studies not reported
  No studies found

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
  No serious adverse effects were reported across five studies that assessed harms (Katchooi 2018; Lombardo 2018; Pavlin 2015; Reiss 2020; Taha 2020).
  5 studies
  GRADE not reported

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Light vibrational forces (LVF) showed no clear difference in rate of orthodontic tooth movement (OTM) during space closure stage… compared with conventional orthodontic appliance treatment (placebo or no adjunct) (low certainty).

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes

  Space closure stage
  MD 0.10 [-0.08, 0.29]
  2 studies · 81 participants
  Low

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

The review found no eligible studies for this question.

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
  Patient-reported need for analgesics | Not reported
  Studies not reported
  No studies found

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Light vibrational forces (LVF) showed no clear difference in patient-reported need for analgesics during first week of initial… compared with conventional orthodontic appliance treatment (placebo or no adjunct) (low certainty).

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes

  First week of initial aligning archwire
  OR 1.64 [0.60, 4.53]
  2 studies · 76 participants
  Low

Low‐level laser therapy vs Conventional orthodontic appliance treatment

It is very uncertain whether low level laser therapy (LLLT) changes rate of orthodontic tooth movement during alignment stage… compared with conventional orthodontic appliance treatment (very low certainty).

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes

  First month of alignment (also second month)
  MD 1.63 [-2.60, 5.86]
  2 studies · 56 participants
  Very low

Low‐level laser therapy vs Conventional orthodontic appliance treatment

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes

  3 and 6 months
  Two studies (62 participants), not pooled. Abellan 2021: no significant difference in molar intrusion at 3 months (1.25 vs 1.72 mm) or 6 months (1.09 vs 1.28 mm), nor rate per month. Hasan 2022: increased intrusion…
  2 studies · 62 participants
  GRADE not reported

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
  Katchooi 2018 (unclear risk of bias): light vibrational forces had no statistically significant (P>0.05) effect on OHRQoL when used with orthodontic aligners.
  1 study · 27 participants
  GRADE not reported

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

The review found no eligible studies for this question.

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
  Total number of orthodontic appliance adjustment appointments required during treatment stage | Not reported
  Studies not reported
  No studies found

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Light vibrational forces (LVF) showed no clear difference in rate of orthodontic tooth movement with removable orthodontic aligners compared with conventional orthodontic appliance treatment (placebo or no adjunct); GRADE not reported.

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes

  Full aligner treatment duration
  MD 0.2 [-1.51, 1.10]
  1 study · 27 participants
  GRADE not reported

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

It is very uncertain whether light-emitting diode (LED) photobiomodulation changes rate of orthodontic tooth movement during space closure stage… compared with conventional orthodontic appliance treatment (very low certainty).

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes

  Space closure (canine retraction)
  MD 0.006 [0, 0.02]
  1 study · 39 participants
  Very low

Low‐level laser therapy vs Conventional orthodontic appliance treatment

• Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
  Abellan 2021 assessed OIIRR using CBCT after intrusion of maxillary molars; no evidence of significant increase or reduction with LLLT. Statistical test results not published.
  1 study
  GRADE not reported