Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

21 questions · 22 findings · 7 reviews · All outcomes

No studies found 7 · 31.8%GRADE not reported 9 · 40.9%Very low 6 · 27.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Betaine (BET) toothpaste (4%) vs SLS toothpaste (1%) and combined BET+SLS toothpaste

Xerostomia (relief of oral dryness) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
  • Rantanen 2003 (crossover): relief of oral dryness BET 44% vs BET+SLS 22% (P = 0.002) vs SLS 18% (P = 0.022) vs reference toothpaste 7% (P < 0.001); betaine-only significantly better than the other toothpastes. No…
    1 study
    GRADE not reported