Findings

What do systematic reviews say?

23 questions · 23 findings · 1 reviews · Breast Cancer

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 4.3%Moderate 16 · 69.6%High 6 · 26.1%

Capecitabine‐containing regimens vs chemotherapy regimens without capecitabine

Objective response rate · people with metastatic breast cancer

Capecitabine‐containing regimens showed no clear difference in objective response rate compared with chemotherapy regimens without capecitabine (moderate certainty).

1 finding from 1 review

Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer 2021 · Cochrane Headline outcomes only
RR 0.97 [0.84, 1.11]
12 studies · 4200 participants
Moderate

Capecitabine‐containing regimens vs chemotherapy regimens without capecitabine

Quality of life · people with metastatic breast cancer

1 finding from 1 review

Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 5 participants
Low

Capecitabine‐containing regimens vs chemotherapy regimens without capecitabine

Pathological complete response · neoadjuvant treatment of ER‐positive vs ER‐negative breast cancer

Capecitabine‐containing regimens showed no clear difference in pathological complete response (pCR): breast and axillary nodes compared with non‐capecitabine‐containing regimens (high certainty).

1 finding from 1 review

Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer 2021 · Cochrane Headline outcomes only
OR 1.12 [0.94, 1.33]
6 studies · 3152 participants
High