Findings

What do systematic reviews say?

23 questions · 23 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 4.3%Moderate 16 · 69.6%High 6 · 26.1%

Capecitabine‐containing regimens vs chemotherapy regimens without capecitabine

PFS: hormone receptor‐negativemedian · people with metastatic breast cancer

Capecitabine‐containing regimens showed no clear difference in PFS: hormone receptor‐negativemedian compared with chemotherapy regimens without capecitabine (moderate certainty).

1 finding from 1 review

Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer 2021 · Cochrane Headline outcomes only
HR 1.01 [0.85, 1.19]
6 studies · 900 participants
Moderate

Capecitabine‐containing regimens vs chemotherapy regimens without capecitabine

Objective response rate · people with metastatic breast cancer

Capecitabine‐containing regimens showed no clear difference in objective response rate compared with chemotherapy regimens without capecitabine (moderate certainty).

1 finding from 1 review

Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer 2021 · Cochrane Headline outcomes only
RR 0.97 [0.84, 1.11]
12 studies · 4200 participants
Moderate

Capecitabine‐containing regimens vs chemotherapy regimens without capecitabine

Quality of life · people with metastatic breast cancer

1 finding from 1 review

Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 5 participants
Low