Findings

What do systematic reviews say?

27 questions · 28 findings · 4 reviews · Infectious Diseases

No studies found 0 · 0%GRADE not reported 1 · 3.6%Very low 0 · 0%Low 17 · 60.7%Moderate 8 · 28.6%High 2 · 7.1%

Neurological sequelae at discharge · children with severe malaria

The intervention showed no clear difference in neurological sequelae at discharge (low certainty).

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
RR 0.84 [0.66, 1.07]
7 studies · 968 participants
Low

Parasite clearance time · children with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 420 participants
Moderate

Fever clearance time · children with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 457 participants
Low

Death · adults with severe malaria

The intervention probably leads to lower death (moderate certainty).

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
RR 0.59 [0.42, 0.83]
4 studies · 716 participants
Moderate

Coma resolution time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 657 participants
Low

Neurological sequelae at discharge · adults with severe malaria

The intervention showed no clear difference in neurological sequelae at discharge (low certainty).

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
RR 2.92 [0.31, 27.86]
1 study · 560 participants
Low

Parasite clearance time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 716 participants
Moderate