Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

27 questions · 27 findings · 9 reviews · Schizophrenia

No studies found 3 · 11.1%GRADE not reported 2 · 7.4%Very low 8 · 29.6%Low 14 · 51.9%Moderate 0 · 0%High 0 · 0%

COMPUTER‐ASSISTED COGNITIVE REMEDIATION PROGRAMME (CACR) vs COMPUTER GAMES (CG, all short‐term)

Leaving the study early · Adolescents with psychosis

It is very uncertain whether COMPUTER‐ASSISTED COGNITIVE REMEDIATION PROGRAMME (CACR) changes leaving the study early: For any reason compared with COMPUTER GAMES (CG, all short‐term) (very low certainty).

1 finding from 1 review

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)

Leaving the study early · Adolescents with psychosis

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) showed no clear difference in leaving the study early: For any reason compared with NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term) (low certainty).

1 finding from 1 review

COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) vs TAU

Leaving the study early · Adolescents with psychosis

It is very uncertain whether COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) changes leaving the study early: For any reason compared with TAU (all short‐term) (very low certainty).

1 finding from 1 review

INTEGRATED MODELS OF CARE vs usual care

Substance use: any change ‐ Alcohol use (not in remission) · people with both severe mental illness and substance misuse

Integrated models of care showed no clear difference in substance use: any change ‐ Alcohol use (not in remission) compared with standard care (low certainty).

1 finding from 1 review

INTEGRATED MODELS OF CARE vs usual care

Substance use: any change ‐ Drug use (not in remission) · people with both severe mental illness and substance misuse

Integrated models of care showed no clear difference in substance use: any change ‐ Drug use (not in remission) compared with standard care (low certainty).

1 finding from 1 review